Research Center Pharmaceutical Engineering (RCPE) (98888)

  • 8010

    Inffeldgasse 13 Graz

    Austria

Research Output 1991 2019

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Conference contribution
2018

Benchmarking a Novel 0-D Model Against Data from Two-Fluid Model Simulations of a Wet Fluidized Bed

Radl, S., Salehi, M. & Askarishahi, M., 29 Oct 2018, AIChE Annual Meeting 2018.

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Open Access
File
benchmarking
fluid
simulation
droplet
spray
2017

Rapid and Lossless Screening of Hot Melt Extruded Formulations

Treffer, D. F., Hörmann, T. & Troiß, A., 30 Jun 2017, Book of Abstracts of Annual Meeting of the Pharmaceutical Solid State Research Cluster. Graz

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

2016

In-situ observation of the transformation of amorphous calcium phosphate to crystalline hydroxyapatite

Stammeier, J. A., Hippler, D., Mavromatis, V., Sacher, S. & Dietzel, M., 2016, Geophysical Research Abstracts: EGU General Assembly 2016 Abstracts. European Geosciences Union, Vol. 18. p. 17043-17043 EGU2016-17043

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

The Virtual Sandbox

Wu, M., Reichel, E., Eck, J., Khinast, J. & Radl, S., 31 Mar 2016, 3rd Austrian Particle Forum.

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

File
sand
geometry
simulation
material
project
2015

Carrier-based Dry Powder Inhalation Part I: Impact of Carrier Modification on Capsule Filling Processability and in vitro Aerodynamic Performance

Zellnitz, S., Faulhammer, E., Wahl, V., Paudel, A. & Khinast, J., 2015, (Accepted/In press) Drug Delivery to the Lungs - DDL26 - Book of abstracts. .

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Carrier-based Dry Powder Inhalation Part II: Impact of carrier material and API processing on the inter-particulate surface interactions in adhesive mixtures for inhalation

Zellnitz, S., Faulhammer, E., Wahl, V., Khinast, J. & Paudel, A., 2015, (Accepted/In press) Drug Delivery to the Lungs - DDL26 - Book of abstracts. .

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Crystallization kinetics of inhalable size amorphous salbutamol as a function of relative humidity and temperature

Zellnitz, S., Narygina, O., Resch, C., Schröttner, H. & Paudel, A., 2015, (Accepted/In press) European Aerosol Conference (EAC 2015) - Proceeding. .

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Detailed Understanding of the Blending of Wet Powders and the Liquid Distribution Therein

Wu, M., Mohan, B., Khinast, J. & Radl, S., 17 Mar 2015, ProcessNet, Vortragsprogramm Grenzflächenbestimmte Systeme und Prozesse, Magdeburg,2015. Magdeburg

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Powders
Liquids
Granulation
Direct numerical simulation
Finite difference method

Die Trocknung partikelbeladener Pasten

Brenn, G., Steiner, H., Planchette, C., Kondor, I. & Mercuri, A., 2015, Proceedings ProcessNet Meeting of Experts "Drying Technology''. ., p. 34-34

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

EXTRACTABLES AND LEACHABLES FROM FILTER MATERIAL AND THEIR IMPACT ON PROTEIN FORMULATION

Wahl, V., Wieser, J., Mohr, S., Khinast, J. & Paudel, A., 2015, Programme & Abstracts. Ghent: ., p. 114-115

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Micro-Pelletizing of Pharmaceutical HME Formulations Using a Die Face Pelletizer

Witschnigg, A., Koscher, G., Treffer, D. F., Mürb, R., Laske, S. & Khinast, J., 2015, (Accepted/In press) Polymer Processing Society 2015. .

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Moisture induced changes in secondary structure and crystallinity of human fibrinogen powders

Wahl, V., Scheibelhofer, O., Rößl, U., Leitgeb, S., deBeer, T. & Khinast, J., 2015, Abstracts Poster. Vienna: ., p. 186-187

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Prozessentwicklung zur Herstellung schmelzextrudierter pharmazeutischer Produkte

Treffer, D. F., Hörmann, T., Koscher, G. & Khinast, J., 3 Dec 2015, Konferenzband: 41. Deutsche Compoundiertagung - Prozessoptimierung an Compoundieranlagen. Nürnberg

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

2014

A Novel Simulation Approach for Hot Melt Extrusion

Eitzlmayr, A., Matic, J., Koscher, G. & Khinast, J., 2014, Book of Abstracts. Graz: ., p. 21-21

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Die Face Pelletizing of Sticky HME Formulations

Treffer, D. F., Koscher, G. & Khinast, J., 2014, 6th International Congress on Pharmaceutical Engineering - Book of Abstracts. ., p. 7-7

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Die Face Pelletizing of Sticky HME Formulations

Treffer, D. F., Koscher, G. & Khinast, J., 2014, (Accepted/In press) Conference Proceedings. .

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearch

Direct Simulation of Film Flow on Spheres to Investigate Liquid Bridge Formation

Wu, M., Khinast, J. & Radl, S., 17 Nov 2014, AIChE Annual Meeting 2014. Atlanta, (USA)

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Investigation of surface modified glass beads as potential carriers in dry powder inhalers

Zellnitz, S., Schröttner, H., Kappl, M. & Urbanetz, N. A., 2014, Book of abstracts. Graz: ., p. 77-77

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Optical coherence tomography data processing for in-line monitoring of a pharmaceutical film-coating process

Markl, D., Hannesschläger, G., Sacher, S., Buchsbaum, A. & Khinast, J., 2014, Proceedings of the 10th Minisymposium Verfahrenstechnik. ., p. 142-145

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Real-time data processing for in-line monitoring of a pharmaceutical coating process by optical coherence tomography

Markl, D., Ziegler, J., Hannesschläger, G., Sacher, S., Buchsbaum, A., Leitner, M. & Khinast, J., 2014, Biophotonics: Photonic Solutions for Better Health Care IV. ., Vol. 9129. p. 1-12 (Proceeding of SPIE).

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Scale−Bridging Models for Transfer of Liquid in Dense Particle Beds

Mohan, B., Wu, M., Sundaresan, S., Khinast, J. & Radl, S., 16 Nov 2014, AIChE Annual Meeting. Atlanta, (USA)

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Open Access
File

Scaling up a Capsule Filling Process for Inhalation Dosage Forms

Llusa, M., Faulhammer, E., Khinast, J., Lawrence, S., Biserni, S. & Calzolari, V., 2014, (Accepted/In press) Scaling up a Capsule Filling Process for Inhalation Dosage Forms. .

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Surface coverage of surface modified glass beads as model carriers in dry powder inhalers influences the FPF

Zellnitz, S., Schröttner, H. & Urbanetz, N. A., 2014, Book of abstracts. ., p. 24-24

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Tailoring drug delivery to the lung by using surface modified glass beads as model carrier

Zellnitz, S., Kappl, M. & Urbanetz, N. A., 2014, Site-specific and controlled delivery. Kiel: ., p. 21-21

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Tailoring drug detachment by surface modification of glass beads as model carrier in dry powder inhalers

Zellnitz, S., Kappl, M. & Urbanetz, N. A., 2014, Conference Proceeding. ., p. xxx-xxx

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

The effects of powder compressibility and the ratio between the powder bed’s height and the length of the dosing chamber on plug densification

Llusa, M., Faulhammer, E., Khinast, J., Lawrence, S., Biserni, S. & Calzolari, V., 2014, (Accepted/In press) The effects of powder compressibility and the ratio between the powder bed’s height and the length of the dosing chamber on plug densification. .

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

The influence of residual water on the secondary structure and crystallinity of freeze dried fibrinogen

Wahl, V., Scheibelhofer, O., Rößl, U., Leitgeb, S., deBeer, T. & Khinast, J., 2014, Book of Abstracts. ., p. 22-23

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

The Simulation of Mixing and Free Surface Flows in Co-Rotating Twin-Screw Extruders

Eitzlmayr, A., Kondor, I., Matic, J., Koscher, G. & Khinast, J., 2014, 2014 AIChE Annual Meeting Conference Proceedings. ., p. 0-0

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Towards A Refined Model for Liquid Bridge Volume Between Wet Particles

Wu, M., Khinast, J. & Radl, S., 20 Jul 2014, 11th World Congress on Computation Mechanics (WCCM XI). Barcelona, Spain

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Trocknung partikelbeladener Pasten (drying of particle-laden pastes)

Brenn, G., Steiner, H., Planchette, C., Kondor, I., Mercuri, A. & Scharrer, G., 2014, Proc. ProcessNet Meeting of Experts "Heat and Mass Transfer''. ., p. paper-5

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

2013

A multipoint measurement spectrometer for monitoring pharmaceutical processes

Scheibelhofer, O., Sacher, S., Menezes, J. C., Kerschhaggl, P. & Khinast, J., 2013, NIR 2013 Proceedings. ., p. 393-396

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

A New Boundary Treatment for Complex Geometries in Smoothed Particle Hydrodynamics

Eitzlmayr, A., Radl, S., Kloss, C., Koscher, G. & Khinast, J., 2013, 2013 AIChE Annual Meeting Conference Proceedings. ., p. 0-0

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Bioreactor simulation with Cuda

Witz, C., Tantikul, T. & Khinast, J. G., 1 Jan 2013, North American Mixing Forum 2013 - Core Programming Area at the 2013 AIChE Annual Meeting: Global Challenges for Engineering a Sustainable Future. American Institute of Chemical Engineers, p. 32-33 2 p.

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Generic Drugs
Bioreactors

Bioreactor simulation with CUDA

Witz, C., Tantikul, T. & Khinast, J., 1 Jan 2013, Pharmaceutical Discovery, Development and Manufacturing Forum 2013 - Core Programming Area at the 2013 AIChE Annual Meeting: Global Challenges for Engineering a Sustainable Future. American Institute of Chemical Engineers, p. 67-68 2 p.

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Bioreactors
Equipment and Supplies
Generic Drugs
Buoyancy
Bubbles (in fluids)

Characterisation of screen printable pastes and resulting thick films: application to electrochemical sensors

Planchette, C. & Brenn, G., 2013, Proceedings 9th European Congress of Chemical Engineering. ., p. abstract-458

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Characterization of physically modified glass beads as potential carrier particles in dry powder inhalates

Zellnitz, S., Redlinger-Pohn, J. D., Schröttner, H., Kappl, M. & Urbanetz, N. A., 2013, 9. Minisymposium der Verfahrenstechnik, Book of Abstracts. ., p. 262-265

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearch

Einfluss des Restwassergehaltes auf das Aggregationsverhalten lyophilisierter Proteinbatches

Wahl, V., Piller, M., Leitgeb, S. & Khinast, J., 2013, Book of Abstracts. ., p. 231-233

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Injection Moulding as a One-Stop-Production to Produce Pharmaceutical Dosage Forms

Treffer, D. F., Eggenreich, K., Schrank, S., Koscher, G., Roblegg, E. & Khinast, J., 2013, (Accepted/In press) Conference Proceedings. .

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearch

Investigation of temperature dependence of tissue relaxation parameters for post-mortem imaging

Kruisz, J., Petrovic, A., Stollberger, R. & Scheurer, E., 2013, International Society for Magnetic Resonance in Medicine: Scientific Meeting & Exhibition. ., p. 2469-2469

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Manufacturing of Low Fill Weight Capsules Using a Nozzle Dosator Capsule Filling Machine

Llusa, M., Faulhammer, E., Khinast, J., Lawrence, S., Biserni, S., Calzolari, V. & Fink, M., 2013, (Accepted/In press) Manufacturing of Low Fill Weight Capsules Using a Nozzle Dosator Capsule Filling Machine. .

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Nano-Extrusion: Herstellung einer festen nanopartikulären Formulierung durch das Verarbeiten von Nanosuspensionen mittels Schmelzextrusion

Baumgartner, R., Khinast, J. & Roblegg, E., 2013, 9. Minisymposium Verfahrenstechnik, 17.04.-18.04.2013, Montanuniversität Leoben, Book of Abstracts. Leoben: Verlag der Montanuniversität Leoben, p. 97-101

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Open Access
File

Optical coherence tomography for non-destructive analysis of coatings in pharmaceutical tablets

Markl, D., Hannesschläger, G., Sacher, S., Khinast, J. & Leitner, M., 2013, Optical Methods for Inspection, Characterization, and Imaging of Biomaterials. Ferraro, P. (ed.). ., Vol. 8792. p. 879202-879202 (SPIE Proceedings).

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Preparation of adhesive mixtures of surface modified glass beads as model carriers in dry powder inhalers and spray dried salbutamol sulphate

Zellnitz, S., Schröttner, H., Kappl, M. & Urbanetz, N. A., 2013, 2013 American Institute of Chemical Engineers (AIChE) Annual Meeting. online: ., p. xxx-xxx

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Simulation of Mixing in Hot Melt Extruders Using Smoothed Particle Hydrodynamics

Eitzlmayr, A., Radl, S., Koscher, G. & Khinast, J., 2013, North American Mixing Forum 2013 - Core Programming Area at the 2013 AIChE Annual Meeting. American Institute of Chemical Engineers, p. 66-67

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Surface modified model carrier particles for the use in dry powder inhalates

Zellnitz, S., Redlinger-Pohn, J. D., Schröttner, H., Kappl, M. & Urbanetz, N. A., 2013, PARTEC - International Congress on Particle Technology. ., p. xxx-xxx

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearch

The Effect of the Ratio between the Powder Bed’s Height and the Length of the Dosing Chamber and the Speed of Capsule Filling on Plug Density and Capsule Weight Variability

Llusa, M., Faulhammer, E., Khinast, J., Scharrer, G., Lawrence, S., Biserni, S. & Calzolari, V., 2013, (Accepted/In press) The Effect of the Ratio between the Powder Bed’s Height and the Length of the Dosing Chamber and the Speed of Capsule Filling on Plug Density and Capsule Weight Variability. .

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Understanding the mixing behavior of mechanically modified glass beads as model carriers in DPIs and salbutamol sulphate

Zellnitz, S., Schröttner, H., Kappl, M. & Urbanetz, N. A., 2013, (Accepted/In press) Drug Delivery to the Lung (DDL24). .

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Untersuchung des Einflusses von Alkohol auf lipophile schmelzextrudierte Pellets

Jedinger, N., Koscher, G., Khinast, J. & Roblegg, E., 2013, 9. Minisymposium der Verfahrenstechnik, 17. und 18. April 2013, Montanuniversität Leoben, Book of Abstracts. Leoben: Verlag der Montanuniversität Leoben, p. 138-142

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

2012

Analysis of drug-packaging interactions via molecular dynamics (MD) simulation

Feenstra, P., Brunsteiner, M. & Khinast, J., 2012, Extractables & Leachables Europe 2012. Shawbury, Shrewsbury, Shropshire SY4 4NR, UK: Smithers Information Ltd., p. 12-1-12-10

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearch

Characterizing critical protein powder parameters for optimization of further processing

Wahl, V., Leitgeb, S. & Khinast, J., 2012, Book of Abstracts. ., p. 137-140

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearch