Research Output 1981 2019

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2015

Phosphoryl transfer from α-D-glucose 1-phosphate catalyzed by Escherichia coli sugar-phosphate phosphatases of two protein superfamily types

Wildberger, P., Pfeiffer, M., Brecker, L., Rechberger, G. N., Birner-Gruenberger, R. & Nidetzky, B., 2015, In : Applied and Environmental Microbiology. 81, 5, p. 1559-1572 14 p.

Research output: Contribution to journalArticleResearchpeer-review

glucose 1-phosphate
Sugar Phosphates
sugar phosphates
phosphatase
sugar

Probing of the reaction pathway of human UDP-xylose synthase with site-directed mutagenesis

Eixelsberger, T., Weber, H. & Nidetzky, B., 2015, In : Carbohydrate Research. 416, p. 1-6

Research output: Contribution to journalArticleResearchpeer-review

Structure-activity studies in the development of a hydrazone based inhibitor of adipose-triglyceride lipase (ATGL)

Mayer, N., Schweiger, M., Melcher, M-C., Fledelius, C., Zechner, R., Zimmermann, R. & Breinbauer, R., 2015, In : Bioorganic & Medicinal Chemistry. 23, p. 2904-2916

Research output: Contribution to journalArticleResearchpeer-review

Structure-based mechanism of oleate hydratase from Elizabethkingia meningoseptica

Engleder, M., Pavkov-Keller, T., Emmerstorfer, A., Altijana, H., Schrempf, S., Steinkellner, G., Wriessnegger, T., Leitner, E., Strohmeier, G., Kaluzna, I., Daniel, M., Martin, S., Wallner, S., Macheroux, P., Gruber, K. & Pichler, H., 2015, In : ChemBioChem. 16, p. 1730-1734

Research output: Contribution to journalArticleResearchpeer-review

The Nitrile forming Enzyme 7-Cyano-7-deazaguanine Synthase from Geobacillus kaustophilus: A reverse Nitrilase?

Winkler, M., Dokulil, K., Weber, H., Pavkov-Keller, T. & Wilding, B., 2015, In : ChemBioChem. 16, p. 2373-2378

Research output: Contribution to journalArticleResearchpeer-review

Tracking morphologies at the nanoscale: Self-assembly of an amphiphilic designer peptide into a double helix superstructure

Kornmueller, K., Letofsky-Papst, I., Gradauer, K., Mikl, C., Cacho Nerin, F., Leypold, M., Keller, W., Leitinger, G., Amenitsch, H. & Prassl, R., 2015, In : Nano Research. 8, 6, p. 1822-1833

Research output: Contribution to journalArticleResearchpeer-review

Weighing the Proteasome for Covalent Modifications

Birner-Gruenberger, R. & Breinbauer, R., 2015, In : Chemistry & Biology. 22, p. 315-316

Research output: Contribution to journalArticleResearchpeer-review

α/β Hydrolase Domain-Containing 6 (ABHD6) Degrades the Late Endosomal/Lysosomal Lipid Bis(monoacylglycero)phosphate

Pribasnig, M. A., Mrak, I., Grabner, G. F., Taschler, U., Knittelfelder, O., Scherz, B., Eichmann, T. O., Heier, C., Grumet, L., Kowaliuk, J., Romauch, M., Holler, S., Anderl, F., Wolinski, H., Lass, A., Breinbauer, R., Marsche, G., Brown, J. M. & Zimmermann, R., 2015, In : The Journal of Biological Chemistry. 290, p. 29869-29881

Research output: Contribution to journalArticleResearchpeer-review

2014

BIOCATALYTIC REDUCTION OF CARBOXYLIC ACIDS

Napora, K., Strohmeier, G. & Winkler, M., 2014, In : Biotechnology Journal. 9, p. 822-843

Research output: Contribution to journalArticleResearchpeer-review

Biosynthese der Phenazine

Diederich, C., Leypold, M., Breinbauer, R. & Blankenfeldt, W., 2014, In : Nachrichten aus der Chemie. 62, p. 975-980

Research output: Contribution to journalArticleResearchpeer-review

Collapse of the native structure by a single amino acid exchange in human NAD(P)H:quinone oxidoreductase (NQO1)

Lienhart, W-D., Gudipati, V., Uhl, M. K., Binter, A., Pulido, S., Saf, R., Zangger, K., Gruber, K. & Macheroux, P., 2014, In : The FEBS journal. 281, p. 4691-4704

Research output: Contribution to journalArticleResearchpeer-review

Concise synthesis of C-1-cyano-iminosugars via a new Staudinger/aza Wittig/Strecker multicomponent reaction strategy

Zoidl, M., Müller, B., Torvisco Gomez, A., Tysoe, C., Benazza, M., Siriwardena, A., Withers, S. & Wrodnigg, T., 2014, In : Bioorganic & Medicinal Chemistry Letters. 24, p. 2777-2780

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Discovery of a novel (R)-selective bacterial cupin HNL from Acidobacterium capsulatum ATCC 51196 by a sequence-based approach

Wiedner, R., Gruber, M., Schwab, H. & Steiner, K., 2014, In : Computational and Structural Biotechnology Journal. 10, 16, p. 58-62

Research output: Contribution to journalArticleResearchpeer-review

Enterotoxicity of a nonribosomal peptide causes antibiotic-associated colitis

Schneditz, G., Rentner, J., Roier, S., Pletz, J., Herzog, K. A. T., Brücker, R., Tröger, H., Schild, S., Weber, H., Breinbauer, R., Gorkiewicz, G., Högenauer, C. & Zechner, E. L., 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, p. 13181-13186

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Exploring the new threonine aldolases with broad donor specificity

Lypetska, K., Strohmeier, G. & Breinbauer, R., 2014, In : New biotechnology. 31, p. S87-S87

Research output: Contribution to journalArticleResearchpeer-review

Festphasensynthese (Trendberichte Organische Chemie 2013)

Breinbauer, R., 2014, In : Nachrichten aus der Chemie. 62, p. 273-274

Research output: Contribution to journalArticleResearchpeer-review

Mechanistic study of CMP-Neu5Ac hydrolysis by α2,3-sialyltransferase from Pasteurella dagmatis

Schmoelzer, K., Luley, C., Czabany, T., Ribitsch, D., Schwab, H., Weber, H. & Nidetzky, B., 2014, In : FEBS letters. 588, 25;17, p. 2978-2984

Research output: Contribution to journalArticleResearchpeer-review

More than just a halogenase: modification of fatty acyl moieties by a trifunctional metal enzyme

Pratter, S. M., Ivkovic, J., Birner-Gruenberger, R., Breinbauer, R., Zangger, K. & Straganz, G. D., 2014, In : ChemBioChem. 15, 4, p. 567-574

Research output: Contribution to journalArticleResearchpeer-review

Recent advances and applications of reductive desulfurization in organic synthesis

Rentner, J., Kljajic, M., Offner, L. & Breinbauer, R., 2014, In : Tetrahedron. 70, p. 8983-9027

Research output: Contribution to journalArticleResearchpeer-review

Stereochemistry and Mechanism of Enzymatic and Non-Enzymatic Hydrolysis of Benzylic sec-Sulfate Esters

Toesch, M., Schober, M., Breinbauer, R. & Faber, K., 2014, In : European journal of organic chemistry. p. 3930-3934

Research output: Contribution to journalArticleResearchpeer-review

The Development of a Modular Synthesis of Teraryl-based alpha-Helix Mimetics as Potential Inhibitors of Protein-Protein Interactions

Trobe, M., Peters, M., Grimm, S. H. & Breinbauer, R., 2014, In : Synlett. 25, p. 1202-1214

Research output: Contribution to journalArticleResearchpeer-review

Towards the synthesis of glycosylated dihydrochalcone natural products using glycosyltransferase-catalysed cascade reactions

Gutmann, A., Bungaruang, L., Weber, H., Leypold, M., Breinbauer, R. & Nidetzky, B., 2014, In : Green chemistry. 16, 9, p. 4417-4425

Research output: Contribution to journalArticleResearchpeer-review

2013

A Modular Synthesis of Teraryl based alpha-Helix Mimetics, Part 1: Synthesis of Core Fragments with two Electronically Differentiated Leaving Groups

Peters, M., Trobe, M., Tan, H., Kleineweischede, R. & Breinbauer, R., 2013, In : Chemistry - a European Journal. 19, p. 2442-2449

Research output: Contribution to journalArticleResearchpeer-review

Biocatalytic Methods for C-C bond formation

Lypetska, K. & Gruber, M., 2013, In : ChemCatChem. 5, p. 1248-1272

Research output: Contribution to journalArticleResearchpeer-review

Chemical Synthesis of Hormones, Pheromones and Other Bioregulators (by K. Mori)

Breinbauer, R., 2013, In : Synthesis. 45, p. 978-978

Research output: Contribution to journalArticleResearchpeer-review

Conformational plasticity and ligand binding of bacterial monoacylglycerol lipase

Rengachari, S., Aschauer, P., Schittmayer, M., Mayer, N., Gruber, K., Breinbauer, R., Birner-Gruenberger, R., Dreveny, I. & Oberer, M., 2013, In : The Journal of Biological Chemistry. 288, p. 31093-31104

Research output: Contribution to journalArticleResearchpeer-review

Development of small molecule inhibitors for adipose triglyceride lipase

Mayer, N., Schweiger, M., Romauch, M., Grabner, G. F., Eichmann, T. F., Fuchs, E., Ivkovic, J., Heier, C., Mrak, I., Lass, A., Höfler, G., Fledelius, C., Zechner, R., Zimmermann, R. & Breinbauer, R., 2013, In : Nature chemical biology. 9, p. 785-787

Research output: Contribution to journalArticleResearchpeer-review

Development of small-molecule inhibitors targeting adipose triglyceride lipase

Mayer, N., Schweiger, M., Romauch, M., Grabner, G., Eichmann, T., Fuchs, E., Ivkovic, J., Heier, C., Mrak, I., Lass, A., Höfler, G., Fledelius, C., Zechner, R., Zimmermann, R. & Breinbauer, R., 2013, In : Nature chemical biology. 9, p. 785-787

Research output: Contribution to journalArticleResearchpeer-review

Enantiocomplementary Yarrowia lipolytica Oxidoreductases: Alcohol Dehydrogenase 2 and Short Chain Dehydrogenase/Reductase

Napora, K., Strohmeier, G., Sonavane, M. N., Avi, M., Robins, K. & Winkler, M., 2013, In : Biomolecules. 3, p. 449-460

Research output: Contribution to journalArticleResearchpeer-review

Festphasensynthese (Trendberichte Organische Chemie 2012)

Breinbauer, R., 2013, In : Nachrichten aus der Chemie. 61, p. 280-281

Research output: Contribution to journalArticleResearchpeer-review

Investigation of one-enzyme systems in the w-transaminase-catalyzed synthesis of chiral amines

Fesko, K., Steiner, K., Breinbauer, R., Schwab, H., Schürmann, M. & Strohmeier, G., 2013, In : Journal of molecular catalysis / B. 96, p. 103-110

Research output: Contribution to journalArticleResearchpeer-review

Investigation of one-​enzyme systems in the ω-​transaminase-​catalyzed synthesis of chiral amines

Lypetska (Fesko), K., Steiner, K., Breinbauer, R., Schwab, H., Schuermann, M. & Strohmeier, G., 2013, In : Journal of molecular catalysis / B. 96, p. 103-110 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Transaminases
Amination
Amines
Enzymes
Paracoccus denitrificans

It takes two to tango: Klebsiella oxytoca overgrowth and production of Tilivalline, a cytotoxin, are the key events causing Antibiotic-Associated Hemorrhagic Colitis

Schneditz, G., Rentner, J., Herzog, K. A., Gorkiewicz, G., Roier, S., Schild, S., Breinbauer, R., Zechner, E. & Högenauer, C., 2013, In : Zeitschrift für Gastroenterologie. 51, p. A50-A50

Research output: Contribution to journalArticleResearchpeer-review

One-Pot Deracemization of sec-Alcohols: Enantioconvergent Enzymatic Hydrolysis of Alkyl Sulfates Using Stereocomplementary Sulfatases

Schober, M., Toesch, M., Knaus, T., Strohmeier, G., van Loo, B., Fuchs, M., Hollfelder, F., Macheroux, P. & Faber, K., 2013, In : Angewandte Chemie / International Edition . 52, 11, p. 3277-3279

Research output: Contribution to journalArticleResearchpeer-review

Racemization-Free Chemoenzymatic Peptide Synthesis Enabled by the Ruthenium-Catalyzed Synthesis of Peptide Enol Esters via Alkyne-Addition and Subsequent Conversion Using Alcalase-Cross-Linked Enzyme Aggregates

Schröder, H., Strohmeier, G. A., Leypold, M., Nuijens, T., Quaedflieg, P. J. L. M. & Breinbauer, R., 2013, In : Advanced Synthesis & Catalysis. 355, p. 1799-1807

Research output: Contribution to journalArticleResearchpeer-review

Targeting the Substrate Binding Site of E. coli Nitrile Reductase QueF by Modeling, Substrate and Enzyme Engineering

Wilding, B., Winkler, M., Petschacher, B., Kratzer, R., Egger, S., Steinkellner, G., Lyskowski, A. F., Nidetzky, B., Gruber, K. & Klempier, N., 2013, In : Chemistry - a European Journal. 19, 22, p. 7007-7012

Research output: Contribution to journalArticleResearchpeer-review

YARROWIA LIPOLYTICA DEHYDROGENASE/ REDUCTASE: AN ENZYME TOLERANT FOR LIPOPHILIC COMPOUNDS AND CARBOHYDRATE SUBSTRATES

Napora, K., Wrodnigg, T., Kosmus, P., Thonhofer, M., Robins, K. & Winkler, M., 2013, In : Bioorganic & Medicinal Chemistry Letters. 23, p. 3393-3395

Research output: Contribution to journalArticleResearchpeer-review

2012

Activity-Based Probes for Studying the Activity of Flavin-Dependent Oxidases and for the Protein Target Profiling of Monoamine Oxidase Inhibitors

Krysiak, J. M., Kreuzer, J., Macheroux, P., Hermetter, A., Sieber, S. A. & Breinbauer, R., 2012, In : Angewandte Chemie / International Edition . 51, p. 7035-7040

Research output: Contribution to journalArticleResearchpeer-review

Aktivitätsbasierte Sondenmoleküle zur Untersuchung der Aktivität Flavin-abhängiger Oxidasen und zum Zielprotein-Profiling von Monoaminooxidase-Inhibitoren

Krysiak, J. M., Kreuzer, J., Macheroux, P., Hermetter, A., Sieber, S. A. & Breinbauer, R., 2012, In : Angewandte Chemie. 124, p. 7142-7147

Research output: Contribution to journalArticleResearchpeer-review

An efficient labelling strategy of drug like molecules with functionalized alkyl linkers using CH-activation

Rentner, J. & Breinbauer, R., 2012, In : Chemical Communications. 48, p. 10343-10345

Research output: Contribution to journalArticleResearchpeer-review

Crystallisation of the novel S-adenosyl-L-methionine dependent C-methyltransferase CouO from Streptomyces rishiriensis and preliminary diffraction data analysis. Acta Crystallogr., Sect. F: Struct. Biol. Cryst. Commun.

Lyskowski, A., Tengg, M., Steinkellner, G., Schwab, H., Gruber, M. & Gruber, K., 2012, In : Acta Crystallographica / F. F68, p. 698-700

Research output: Contribution to journalArticleResearchpeer-review

Festphasensynthese (Trendberichte Organische Chemie 2011)

Breinbauer, R., 2012, In : Nachrichten aus der Chemie. 60, 3, p. 286-286

Research output: Contribution to journalArticleResearchpeer-review

Fluorous Iminoalditols act as Effective Pharmacological Chaperones against Gene Products from GLB1 Alleles causing GM1-Gangliosidosis and Morquio B Disease

Fantur, K., Wrodnigg, T., Stütz, A., Pabst, B. M. & Paschke, E., 2012, In : Journal of inherited metabolic disease. 35, 3, p. 495-503

Research output: Contribution to journalArticleResearchpeer-review

Molecular characterization of the C-Methyltransferase NovO of Streptomyces spheroides, a valuable enzyme for performing Friedel-Crafts alkylation

Tengg, M., Stecher, H., Remler, P., Eiteljörg, I., Gruber, M. & Schwab, H., 2012, In : Journal of molecular catalysis / B. 84, p. 2-8

Research output: Contribution to journalArticleResearchpeer-review

NITRILE REDUCTASE FROM GEOBACILLUS KAUSTOPHILUS: A POTENTIAL CATALYST FOR A NEW NITRILE BIOTRANSFORMATION REACTION

Wilding, B., Winkler, M., Kratzer, R., Petschacher, B., Glieder, A. & Klempier, N., 2012, In : Advanced Synthesis & Catalysis. 354, 11-12, p. 2191-2198

Research output: Contribution to journalArticleResearchpeer-review

Structural and mechanistic insight into N-glycan processing by endo-α-mannosidase

Davies, G., Thompson, A., Gloster, T., Williams, R., Hakki, Z., Wennekes, T., Songsrirote, K., Wrodnigg, T., Spreitz, J., Stütz, A., Thomas-Oates, J. & Williams, S., 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, p. 781-786

Research output: Contribution to journalArticleResearchpeer-review

The Amadori Rearrangement as Glycoconjugation Method: Synthesis of Non-natural C-Glycosyl Type Glycoconjugates

Gallas, K., Pototschnig, G., Adanitsch, F., Stütz, A. & Wrodnigg, T., 2012, In : Beilstein Journal of Organic Chemistry . p. 1619-1629

Research output: Contribution to journalArticleResearchpeer-review

The Two Faces of Iminoalditols: Powerful Inhibitors Trigger Glycosidase Activation

Wrodnigg, T. & Stütz, A., 2012, In : Current enzyme inhibition. 8, p. 47-99

Research output: Contribution to journalArticleResearchpeer-review