Research Output 1981 2019

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Poster
2019

A Multi-Enzyme System for the In vitro Reduction of Carboxylic Acids to Aldehydes

Strohmeier, G., Schwarz, A., Eiteljörg, I., Kohrt, J., Howard, R. & Winkler, M., Jul 2019.

Research output: Contribution to conferencePosterResearch

Capsaicin Metabolite Synthesis by Fungal Cytochrome P450

Willim, M., Bachler, T., Schweda, B., Migglautsch, A. K., Glieder, A., Breinbauer, R. & Winkler, M., 14 Feb 2019.

Research output: Contribution to conferencePosterResearch

Chemoselective Cysteine Bioconjugation via Palladium-Mediated Allylation

Schlatzer, T., Kriegesmann, J., Becker, C. F. W. & Breinbauer, R., 18 Jun 2019.

Research output: Contribution to conferencePosterResearchpeer-review

Iodonium-based Probes for the Activity-based Protein Profiling of Oxidoreductases

Breinbauer, R., Kljajic, M., Darnhofer, B., Schittmayer, M., Kollau, A., Mayer, B. & Birner-Grünberger, R., 25 Sep 2019.

Research output: Contribution to conferencePosterResearchpeer-review

Iodonium-based Probes for the Activity-based Protein Profiling of Oxidoreductases

Kljajic, M., Darnhofer, B., Schittmayer, M., Kollau, A., Mayer, B., Birner-Grünberger, R. & Breinbauer, R., 28 Mar 2019.

Research output: Contribution to conferencePosterResearchpeer-review

Towards a new panel of nitrile hydratases

Grill, B., Schwab, H., Glänzer, M., Steinkellner, G., Strohmeier, G., Pogorevcnik, U., Reicher, K., Gruber, K., Donsbach, K. & Winkler, M., 26 Jun 2019.

Research output: Contribution to conferencePosterResearch

2018

Catalytic and substrate promiscuity of engineered l-threonine aldolase

Fesko, K., 2018.

Research output: Contribution to conferencePosterResearchpeer-review

Cyclopentanoid D-Galactosidase Inhibitors and potential Pharmacological Chaperones for GM1-Gangliosidosis

Weber, P., Pabst, B. M., Paschke, E., Schalli, M., Stütz, A., Tschernutter, M., Windischhofer, W., Withers, S. G. & Wrodnigg, T. M., 2018.

Research output: Contribution to conferencePosterResearchpeer-review

CYCLOPENTANOID N-ACETYL-β-D-HEXOSAMINIDASE INHIBITORS

Weber, P., Pabst, B. M., Paschke, E., Schalli, M., Stütz, A., Tschernutter, M., Windischhofer, W., Wolfsgruber, A. & Wrodnigg, T. M., 2018.

Research output: Contribution to conferencePosterResearchpeer-review

Development of Small-Molecule Inhibitors of Adipose Triglyceride Lipase (ATGL)

Migglautsch, A. K., Doler, C. J., Schweiger, M., Mayer, N., Fuchs, E., Grabner, G., Romauch, M., Zechner, R., Zimmermann, R. & Breinbauer, R., 6 Sep 2018.

Research output: Contribution to conferencePosterResearchpeer-review

From a chelating, non-selective chemical probe to selective MMP-13 inhibitors for the treatment of osteoarthritis

Fürst, R., Choi, J. Y., Knapinska, A. M., Hart, P. J., Fields, G. B. & Roush, W. R., 30 Aug 2018.

Research output: Contribution to conferencePosterResearch

FURANOID CARBASUGARS AS GH 20 HEXOSAMINIDASE INHIBITORS AND POTENTIAL PHARMACOLOGICAL CHAPERONES

Wolfsgruber, A., Nasseri, S. A., Pabst, B. M., Paschke, E., Schalli, M., Stütz, A., Torvisco Gomez, A., Müller, P., Tschernutter, M., Weber, P., Windischhofer, W., Withers, S. G. & Wrodnigg, T. M., 2018.

Research output: Contribution to conferencePosterResearchpeer-review

Palladium-Mediated Allylation of Cysteine for Site-Selective Bioconjugation

Schlatzer, T., Kriegesmann, J., Becker, C. F. W. & Breinbauer, R., 18 Sep 2018.

Research output: Contribution to conferencePosterResearchpeer-review

Palladium-Mediated Allylation of Cysteine for Site-Selective Bioconjugation

Schlatzer, T., Kriegesmann, J., Becker, C. F. W. & Breinbauer, R., 13 Dec 2018.

Research output: Contribution to conferencePosterResearchpeer-review

Palladium-Mediated Allylation of Cysteine for Site-Selective Bioconjugation of Peptides and Proteins

Schlatzer, T., Kriegesmann, J., Schröder, H., Trobe, M., Becker, C. F. W. & Breinbauer, R., 29 Aug 2018.

Research output: Contribution to conferencePosterResearchpeer-review

Pd-Mediated Allylation of Cysteine for Site-Selective Bioconjugation of Peptides and Proteins

Schlatzer, T., Kriegesmann, J., Schröder, H., Trobe, M., Lembacher-Fadum, C., Becker, C. F. W. & Breinbauer, R., 10 Sep 2018.

Research output: Contribution to conferencePosterResearchpeer-review

Synthesis and Biological Characterization of Teraryl-based alpha-Helix-Mimetics

Blesl, J., Vareka, M., Trobe, M. & Breinbauer, R., 26 Jun 2018.

Research output: Contribution to conferencePosterResearch

The monolignol oxidoreductase AtBBE-like protein 15: Characterization, rational engineering and biocatalytic applications.

Daniel, B., Messenlehner, J., Schrittwieser, J. H., Pils, S., Kroutil, W. & Macheroux, P., 28 Aug 2018.

Research output: Contribution to conferencePosterResearchpeer-review

Total Syntheses of Tilivalline and Tilimycin, Cytotoxic Secondary Metabolites of Klebsiella Oxytoca

Lembacher-Fadum, C., Dornisch, E., Pletz, J., Glabonjat, R. A., Martin, F., Neger, M., Högenauer, C., Francesconi, K. A., Kroutil, W., Zangger, K., Zechner, E. L. & Breinbauer, R., 27 Aug 2018.

Research output: Contribution to conferencePosterResearchpeer-review

Whole-cell (+)-ambrein production in the yeast Pichia pastoris

Moser, S., Strohmeier, G. A., Leitner, E., Plocek, T. J., Vanhessche, K. & Pichler, H., 26 Jun 2018.

Research output: Contribution to conferencePosterResearch

2017

A General and Direct Reductive Amination of Aldehydes and Ketones with Electron-Deficient Anilines

Berg, B., Pletz, J. & Breinbauer, R., 3 Sep 2017.

Research output: Contribution to conferencePosterResearch

Application of hydratases for flavor and fragrance synthesis

Engleder, M., Pavkov-Keller, T., Emmerstorfer, A., Hromic, A., Schrempf, S., Steinkellner, G., Wriessnegger, T., Leitner, E., Strohmeier, G., Kaluzna, I., Daniel, M., Schürmann, M., Wallner, S., Macheroux, P., Pichler, H. & Gruber, K., 14 Nov 2017.

Research output: Contribution to conferencePosterResearchpeer-review

Application of hydratases for flavour and fragrance synthesis

Engleder, M., Pavkov-Keller, T., Emmerstorfer, A., Altijana, H., Schrempf, S., Steinkellner, G., Wriessnegger, T., Leitner, E., Strohmeier, G., Kaluzna, I., Mink, D., Schürmann, M., Wallner, S., Macheroux, P., Gruber, K. & Pichler, H., 20 Sep 2017.

Research output: Contribution to conferencePosterResearchpeer-review

Chemoenzymatic Synthesis of α-Quaternary Stereogenic α-Amino Acids

Blesl, J., Strohmeier, G., Fesko, K. & Breinbauer, R., 30 Aug 2017.

Research output: Contribution to conferencePosterResearch

Chemoenzymatic Synthesis of α-Quaternary Stereogenic α-Amino Acids

Blesl, J., Strohmeier, G., Fesko, K. & Breinbauer, R., 25 Sep 2017.

Research output: Contribution to conferencePosterResearch

Development of small-molecule inhibitors of Adipose Triglyceride Lipase (ATGL)

Migglautsch, A. K., Doler, C. J., Schweiger, M., Mayer, N., Fuchs, E., Grabner, G., Romauch, M., Zechner, R., Zimmermann, R. & Breinbauer, R., 25 Sep 2017.

Research output: Contribution to conferencePosterResearch

Experimental Pharmacological Chaperones for Lysosomal Glycosidase Mutants

Schalli, M., Thonhofer, M., Lebl, R., Weber, P., Tysoe, C., Pabst, B., Paschke, E., Stütz, A., Tschernutter, M., Windischhofer, W., Withers, S. G., Wrodnigg, T. M. & Zoidl, M., 2017.

Research output: Contribution to conferencePosterResearchpeer-review

Furanoid Carbasugars as Hexosaminidase Inhibitors and Potential Pharmacological Chaperones

Weber, P., Lebl, R., Müller, S., Pabst, B., Paschke, E., Schalli, M., Stütz, A., Tschernutter, M., Tysoe, C., Windischhofer, W., Withers, S. G., Wrodnigg, T. M. & Zoidl, M., Jul 2017.

Research output: Contribution to conferencePosterResearchpeer-review

Furanoid Carbasugars as Hexosaminidase Inhibitors and Potential Pharmacological Chaperones (D-galacto)

Weber, P., Lebl, R., Schalli, M., Schuh, L., Stütz, A., Withers, S. G., Wrodnigg, T. M. & Zoidl, M., 2017.

Research output: Contribution to conferencePosterResearchpeer-review

Investigation of an Unexpected Cyclization During a Horner-Wadsworth-Emmons Reaction

Lembacher-Fadum, C., Ivkovic, J., Pletz, J., Ratzenböck, K., Maringer, M., Weber, H., Fischer, R. & Breinbauer, R., 5 Sep 2017.

Research output: Contribution to conferencePosterResearchpeer-review

Kinetic studies of inhibition of hDPP3 by hydroxyethylene transition state peptidomimetics

Jha, S., Ivkovic, J., Kumar, P., Taschler, U., Zimmermann, R., Gruber, K., Breinbauer, R. & Macheroux, P., 3 Feb 2017.

Research output: Contribution to conferencePosterResearch

Monitoring of Chemical Processes throughout Interaction of Coniferyl Aldehyde with Thermoanaerobacter mathranii by Liquid-State 1H NMR Spectroscopy

Wöss, K., Weber, H., Olschowski, P. & Weber, H. K., 28 Mar 2017.

Research output: Contribution to conferencePosterResearch

New Dansylated Derivates of 4-epi-Isofagomine

Thonhofer, M., Schalli, M., Tysoe, C., Pabst, B., Lebl, R., Paschke, E., Stütz, A., Tschernutter, M., Weber, P., Windischhofer, W., Withers, S. G., Wrodnigg, T. M. & Zoidl, M., 2017.

Research output: Contribution to conferencePosterResearchpeer-review

New Palladium Catalyzed Approach towards 5-membered Nitrogen-containing Heterocycles

Kljajic, M. & Breinbauer, R., 22 Jul 2017.

Research output: Contribution to conferencePosterResearch

New “old yellow enzyme”: a reductive C-C bond formation using engineered enoate reductase

Heckenbichler, K., Schweiger, A. K., Gruber, K., Macheroux, P. & Breinbauer, R., 9 Jul 2017.

Research output: Contribution to conferencePosterResearch

N-Substituted 5-amino-1-hydroxymethyl-Cyclopentanetriols: A new Family of Promotors for GM1-Gangliosidosis Related Human Lysosomal β-Galactosidase Mutants

Schalli, M., Weber, P., Tysoe, C., Pabst, B., Lebl, R., Paschke, E., Stütz, A., Tschernutter, M., Windischhofer, W., Withers, S. G., Wrodnigg, T. M. & Zoidl, M., 2017.

Research output: Contribution to conferencePosterResearchpeer-review

Peptidomimetic transition state inhibitors as chemical probes to explore in-vivo role of dipeptidyl peptidase 3

Jha, S., Ivkovic, J., Kumar, P., Taschler, U., Zimmermann, R., Gruber, K., Breinbauer, R. & Macheroux, P., Jul 2017.

Research output: Contribution to conferencePosterResearch

Pharmacological Inhibition of Adipose Triglyceride Lipase corrects High-Fat Diet-Induced Insulin Resistance and Hepatosteatosis in mice

Breinbauer, R., Doler, C. J., Schweiger, M., Migglautsch, A. K., Mayer, N., Grabner, G., Zechner, R. & Zimmermann, R., 13 Sep 2017.

Research output: Contribution to conferencePosterResearchpeer-review

Pharmacological inhibition of ATGL (Adipose Triglyceride Lipase) corrects high-fat diet-induced hepatosteatosis in mice

Schweiger, M., Mayer, N., Romauch, M., Grabner, G., Doler, C. J., Migglautsch, A. K., Hütter, S., Kotzbeck, P., Eichmann, T. O., Yamada, S., Knittelfelder, O., Diwoky, C., Lass, A., Zechner, R., Zimmermann, R. & Breinbauer, R., 27 Jun 2017.

Research output: Contribution to conferencePosterResearchpeer-review

Post-Translational Pd-Catalyzed S-Prenylation of Peptides and Proteins

Schlatzer, T., Schröder, H., Trobe, M., Lembacher-Fadum, C., Becker, C. & Breinbauer, R., 28 Sep 2017.

Research output: Contribution to conferencePosterResearchpeer-review

Rescuing the stability and activity of a cancer associated variant of human NQO1 by small molecular chaperones

Strandback, E. S., Lienhart, W-D., Hromic-Jahjefendic, A., Högler, A., Winkler, A., Zangger, K., Dandachi, N., Heitzer, E., Bourgeois, B., Madl, T., Breinbauer, R., Gruber, K. & Macheroux, P., 2017.

Research output: Contribution to conferencePosterResearch

Rescuing the stability and activity of a cancer associated variant of human NQO1 by small molecular chaperones

Strandback, E. S., Lienhart, W-D., Hromic-Jahjefendic, A., Högler, A., Winkler, A., Zangger, K., Dandachi, N., Heitzer, E., Bourgeois, B., Madl, T., Breinbauer, R., Gruber, K. & Macheroux, P., 2017.

Research output: Contribution to conferencePosterResearch

Stabilization of a cancer associated variant of human NQO1 by the use of small-molecular chaperones

Strandback, E. S., Lienhart, W-D., Hromic-Jahjefendic, A., Högler, A., Waltenstorfer, D., Winkler, A., Zangger, K., Dandachi, N., Heitzer, E., Bourgeois, B., Madl, T., Breinbauer, R., Gruber, K. & Macheroux, P., 2017.

Research output: Contribution to conferencePosterResearch

Structure-based reaction mechanism of oleate hydratase from Elizabethkingia meningoseptica

Engleder, M., Pavkov-Keller, T., Emmerstorfer-Augustin, A., Hromic, A., Schrempf, S., Steinkellner, G., Wriessnegger, T., Leitner, E., Strohmeier, G., Kaluzna, I., Daniel, M., Martin, S., Wallner, S., Macheroux, P., Gruber, K. & Pichler, H., 23 Apr 2017.

Research output: Contribution to conferencePosterResearchpeer-review

Hydro-Lyases
Oleic Acid
Hydration
Flavin-Adenine Dinucleotide
Carbon

Substrate specificity of CYP505X from Aspergillus fumigatus

Bachler, T., Alkofer, A., Gralewska, P., Weninger, A., Glieder, A., Breinbauer, R. & Winkler, M., 11 Jul 2017.

Research output: Contribution to conferencePosterResearch

SYNTHESIS AND CHARACTERIZATION OF SUGAR-BASED TETRAACYLGERMANES

Schuh, L., Haas, M., Schalli, M., Weber, P., Stütz, A., Torvisco Gomez, A. & Stüger, H., 2017.

Research output: Contribution to conferencePosterResearchpeer-review

Synthesis of 5a-C-Extended 4-epi-Isofagomine Derivatives from D-Glyceraldehyde – Powerful Pharmacological Chaperones for GM1-Gangliosidosis

Lebl, R., Thonhofer, M., Tysoe, C., Pabst, B., Paschke, E., Schalli, M., Stütz, A., Tschernutter, M., Weber, P., Windischhofer, W., Withers, S. G., Wrodnigg, T. M. & Zoidl, M., 2017.

Research output: Contribution to conferencePosterResearchpeer-review

Synthesis of an Amphiphilic Oligoaryl-based ApoA1 Mimetic

Dobrounig, P. S. & Breinbauer, R., 29 Jul 2017.

Research output: Contribution to conferencePosterResearchpeer-review