Research Output

2020

All Sugar Based Cellulose Derivatives Synthesized by Azide–Alkyne Click Chemistry

Koschella, A., Chien, C. Y., Iwata, T., Thonhofer, M. S., Wrodnigg, T. M. & Heinze, T., 1 Jan 2020, In : Macromolecular chemistry and physics. 221, 1, 1900343.

Research output: Contribution to journalArticle

Open Access

Co-factor demand and regeneration in the enzymatic one-step reduction of carboxylates to aldehydes in cell-free systems

Strohmeier, G., Schwarz, A., Andexer, J. N. & Winkler, M., 10 Jan 2020, In : Journal of Biotechnology. 307, p. 202-207 14 p.

Research output: Contribution to journalArticle

Festphasen- und Flowsynthese (Trendbericht, Organische Chemie 2019)

Breinbauer, R., 2020, In : Nachrichten aus der Chemie. 68, 3, p. 48-49

Research output: Contribution to journalArticle

Pd/BIPHEPHOS is an Efficient Catalyst for the Pd‐Catalyzed S‐Allylation of Thiols with High n‐Selectivity

Schlatzer, T., Schröder, H., Trobe, M., Lembacher-Fadum, C., Stangl, S., Schlögl, C., Weber, H. & Breinbauer, R., 2020, In : Advanced Synthesis & Catalysis. 362, p. 331-336

Research output: Contribution to journalArticle

Open Access

Stereoselective synthesis of chiral thiol-containing 1,2-aminoalcohols via SmI2-mediated coupling

Doler, C., Friess, M., Lackner, F., Weber, H., Fischer, R. C. & Breinbauer, R., 1 Jan 2020, (Accepted/In press) In : Tetrahedron. 131249.

Research output: Contribution to journalArticle

Open Access

Structure-activity relationship studies for the development of inhibitors of murine adipose triglyceride lipase (ATGL)

Mayer, N., Schweiger, M., Fuchs, E., Migglautsch, A. K., Doler, C., Grabner, G. F., Romauch, M., Melcher, M. C., Zechner, R., Zimmermann, R. & Breinbauer, R., 15 Aug 2020, In : Bioorganic and Medicinal Chemistry. 28, 16, 115610.

Research output: Contribution to journalArticle

Open Access

Synthesis of a Bcl9 Alpha-Helix Mimetic for Inhibition of PPIs by a Combination of Electrooxidative Phenol Coupling and Pd-Catalyzed Cross Coupling

Vareka, M., Dahms, B., Lang, M., Hoang, H. M., Trobe, M., Weber, H., Hielscher, M. H., Waldvogel, S. R. & Breinbauer, R., 2020, In : Catalysts. 10, 3, 9 p., 340.

Research output: Contribution to journalArticle

Open Access
2019

A cell-free in vitro reduction of carboxylate to aldehyde

Schwarz, A., Strohmeier, G., Eiteljörg, I., Kohrt, J., Howard, R. & Winkler, M., Nov 2019.

Research output: Contribution to conferencePoster

A Multi-Enzyme System for the In vitro Reduction of Carboxylic Acids to Aldehydes

Strohmeier, G., Schwarz, A., Eiteljörg, I., Kohrt, J., Howard, R. & Winkler, M., Jul 2019.

Research output: Contribution to conferencePoster

Application of hydrates in industrial biocatalysts

Freudenthaler, J., Engleder, M., Emmerstorfer-Augustin, A., Wriessnegger, T., Pavkov-Keller, T., Steinkellner, G., Leitner, E., Strohmeier, G., Kaluzna, I., Müller, M., Mink, D., Schürmann, M., Pichler, H. & Gruber, K., 18 Nov 2019.

Research output: Contribution to conferencePoster

Biocatalytic Enantioselective Oxidation of Sec-Allylic Alcohols with Flavin-Dependent Oxidases

Gandomkar, S., Jost, E., Loidolt, D., Swoboda, A., Pickl, M., Elaily, W., Daniel, B., Fraaije, M. W., Macheroux, P. & Kroutil, W., 19 Nov 2019, In : Advanced Synthesis and Catalysis. 361, 22, p. 5264-5271 8 p.

Research output: Contribution to journalArticle

Open Access

Capsaicin Metabolite Synthesis by Fungal Cytochrome P450

Willim, M., Bachler, T., Schweda, B., Migglautsch, A. K., Glieder, A., Breinbauer, R. & Winkler, M., 14 Feb 2019.

Research output: Contribution to conferencePoster

Carbohydrates@MOFs

Astria, E., Thonhofer, M. S., Ricco, R., Liang, W., Angela, C., Tarzia, A., Alt, K., Hagemeyer, C., Rattenberger, J., Schröttner, H., Wrodnigg, T. M., Amenitsch, H., Huang, D., Doonan, C. & Falcaro, P., 1 Jun 2019, In : Materials Horizons. 6, 5, p. 969-977 9 p.

Research output: Contribution to journalArticle

Open Access

Chemoselective Cysteine Bioconjugation via Palladium-Mediated Allylation

Schlatzer, T., Kriegesmann, J., Becker, C. F. W. & Breinbauer, R., 18 Jun 2019.

Research output: Contribution to conferencePoster

Comparison of L-threonine aldolase variants in the aldol and retro-aldol reactions

Fesko, K., 1 Jan 2019, In : Frontiers in Bioengineering and Biotechnology. 7, MAY, 119.

Research output: Contribution to journalArticle

Cytochrome P450 mediated hydroxylation of ibuprofen using Pichia pastoris as biocatalyst

Rinnofner, C., Kerschbaumer, B., Weber, H., Glieder, A. & Winkler, M., Nov 2019.

Research output: Contribution to conferencePoster

Cytochrome P450 mediated hydroxylation of ibuprofen using Pichia pastoris as biocatalyst

Rinnofner, C., Kerschbaumer, B., Weber, H., Glieder, A. & Winkler, M., Apr 2019.

Research output: Contribution to conferencePoster

Open Access

Deciphering the enzymatic mechanism of sugar ring contraction in UDP-apiose biosynthesis

Savino, S., Borg, A. J. E., Dennig, A., Pfeiffer, M., De Giorgi, F., Weber, H., Dubey, K. D., Rovira, C., Mattevi, A. & Nidetzky, B., 1 Dec 2019, In : Nature Catalysis. 2, 12, p. 1115-1123 9 p.

Research output: Contribution to journalArticle

Development of Small-molecule inhibitors of Adipose Triglyceride Lipase (ATGL)

Migglautsch, A. K., Guttenberger, N., Schweiger, M., Grabner, G. F., Mayer, N., Zechner, R., Zimmermann, R. & Breinbauer, R., 11 Jun 2019.

Research output: Contribution to conferencePoster

Exploring the Biocatalytic Potential of a Self‐Sufficient Cytochrome P450 from Thermothelomyces thermophila

Fürst, M. J. L. J., Kerschbaumer, B., Rinnofner, C., Migglautsch, A. K., Winkler, M. & Fraaije, M. W., 2019, In : Advanced Synthesis & Catalysis. 361, 11, p. 2487-2496

Research output: Contribution to journalArticle

Open Access

Festphasen- und Flowsynthese (Trendbericht, Organische Chemie 2018)

Breinbauer, R., 2019, In : Nachrichten aus der Chemie. 67, 3, p. 53-54

Research output: Contribution to journalArticle

High-Performance Hybrid Computing for Bioinformatic Analysis of Protein Superfamilies

Suplatov, D., Sharapova, Y., Shegay, M., Popova, N., Fesko, K., Voevodin, V. & Švedas, V., 1 Jan 2019, Supercomputing - 5th Russian Supercomputing Days, RuSCDays 2019, Revised Selected Papers. Voevodin, V. & Sobolev, S. (eds.). Springer, p. 249-264 16 p. (Communications in Computer and Information Science; vol. 1129 CCIS).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Influence of base-catalyzed organosolv fractionation of larch wood sawdust on fraction yields and lignin properties

Hochegger, M., Trimmel, G., Cottyn-Boitte, B., Cézard, L., Majira, A., Schober, S. & Mittelbach, M., 1 Dec 2019, In : Catalysts. 9, 12, 996.

Research output: Contribution to journalArticle

Open Access

Iodonium-based Probes for the Activity-based Protein Profiling of Oxidoreductases

Kljajic, M., Darnhofer, B., Schittmayer, M., Kollau, A., Mayer, B., Birner-Grünberger, R. & Breinbauer, R., 28 Mar 2019.

Research output: Contribution to conferencePoster

Iodonium-based Probes for the Activity-based Protein Profiling of Oxidoreductases

Breinbauer, R., Kljajic, M., Darnhofer, B., Schittmayer, M., Kollau, A., Mayer, B. & Birner-Grünberger, R., 25 Sep 2019.

Research output: Contribution to conferencePoster

Klebsiella oxytoca enterotoxins tilimycin and tilivalline have distinct host DNA-damaging and microtubule-stabilizing activities

Unterhauser, K., Pöltl, L., Schneditz, G., Kienesberger, S., Glabonjat, R. A., Kitsera, M., Pletz, J., Josa-Prado, F., Dornisch, E., Lembacher-Fadum, C., Roier, S., Gorkiewicz, G., Lucena, D., Barasoain, I., Kroutil, W., Wiedner, M., Loizou, J. I., Breinbauer, R., Díaz, J. F., Schild, S. & 2 others, Högenauer, C. & Zechner, E. L., 26 Feb 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 9, p. 3774-3783 10 p.

Research output: Contribution to journalArticle

Open Access

Labeling and Natural Post-Translational Modification of Peptides and Proteins via Chemoselective Pd-Catalyzed Prenylation of Cysteine

Schlatzer, T., Kriegesmann, J., Schröder, H., Trobe, M., Lembacher-Fadum, C., Santner, S., Kravchuk, A., Becker, C. F. W. & Breinbauer, R., 2019, In : Journal of the American Chemical Society. 141, 37, p. 14931-14937

Research output: Contribution to journalArticle

Open Access

Metabolic disease and ABHD6 alter the circulating bis(monoacylglycerol)phosphate profile in mice and humans

Grabner, G. F., Fawzy, N., Pribasnig, M. A., Trieb, M., Taschler, U., Holzer, M., Schweiger, M., Wolinski, H., Kolb, D., Horvath, A., Breinbauer, R., Rülicke, T., Rabl, R., Lass, A., Stadlbauer, V., Hutter-Paier, B., Stauber, R. E., Fickert, P., Zechner, R., Marsche, G. & 2 others, Eichmann, T. O. & Zimmermann, R., 1 Jan 2019, In : Journal of lipid research. 60, 5, p. 1020-1031 12 p.

Research output: Contribution to journalArticle

Open Access

New lectin ligands: Testing of Amadori rearrangement products with a series of mannoside-specific lectins

Prasch, H., Hojnik, C., Lindhorst, T. K., Didak, B., Landemarre, L. & Wrodnigg, T. M., 1 Mar 2019, In : Carbohydrate Research. 475, p. 65-68 4 p.

Research output: Contribution to journalArticle

Open Access

Recombinant (+)-ambrein production: Saccharomyces cerevisiae vs. Pichia pastoris

Moser, S., Schneider, J., Strohmeier, G., Leitner, E., Plocek, T. J., Vanhessche, K. & Pichler, H., 18 Nov 2019.

Research output: Contribution to conferencePoster

Selective Formation of 4,4′-Biphenols by Anodic Dehydrogenative Cross- and Homo-Coupling Reaction

Dahms, B., Kohlpaintner, P. J., Wiebe, A., Breinbauer, R., Schollmeyer, D. & Waldvogel, S. R., 21 Feb 2019, In : Chemistry - a European Journal. 25, 11, p. 2713-2716 4 p.

Research output: Contribution to journalArticle

Selective hydration of oleic acid derivatives

Pichler, H., Schuermann, M., Schuetz, R., Engleder, M. & Strohmeier, G., 12 Dec 2019, IPC No. C11C 1/04 (2006.01), WIPO, Patent No. WO 2019/234043 A1, 4 Jun 2019, Priority date 4 Jun 2018, Priority No. 00706/18

Research output: Patent

Site-Selective Bioconjugation via Palladium-Mediated Allylation of Cysteine

Schlatzer, T., Kriegesmann, J., Becker, C. F. W. & Breinbauer, R., 5 Dec 2019.

Research output: Contribution to conferencePoster

Stereoselective Biotransformations of Cyclic Imines in Recombinant Cells of Synechocystis sp. PCC 6803

Buechsenschuetz, H. C., Vidimce-Risteski, V., Eggbauer, B., Schmidt, S., Winkler, C. K., Schrittwieser, J. H., Kroutil, W. & Kourist, R., 2019, In : ChemCatChem. 12, 3, p. 726-730

Research output: Contribution to journalArticle

Synthesis and biological evaluation of cis-restrained carbocyclic combretastatin A-4 analogs: Influence of the ring size and saturation on cytotoxic properties

Nowikow, C., Fürst, R., Kauderer, M., Dank, C., Schmid, W., Hajduch, M., Rehulka, J., Gurska, S., Mokshyna, O., Polishchuk, P., Zupko, I., Dzubak, P. & Rinner, U., 1 Oct 2019, In : Bioorganic & Medicinal Chemistry. 2019, 27

Research output: Contribution to journalArticle

Synthesis of 2-Pyrrolidinones by Palladium-Catalyzed [3+2] Cycloaddition of Isocyanates

Kljajic, M., Schlatzer, T. & Breinbauer, R., 2019, In : Synlett. 30, 5, p. 581-585 5 p.

Research output: Contribution to journalArticle

Synthesis of modified 1,5‑imino‑d‑xylitols as ligands for lysosomal β‑glucocerebrosidase

Zoidl, M., Wolfsgruber, A., Schalli, M., Nasseri, S. A., Weber, P., Stütz, A., Withers, S. G. & Wrodnigg, T. M., 2019, In : Monatshefte für Chemie = Chemical monthly. 150, 5, p. 831-842 12 p.

Research output: Contribution to journalArticle

The CXCR4-CXCL12-Axis Is of Prognostic Relevance in DLBCL and Its Antagonists Exert Pro-Apoptotic Effects In Vitro

Pansy, K., Feichtinger, J., Ehall, B., Uhl, B., Sedej, M., Roula, D., Pursche, B., Wolf, A., Zoidl, M., Steinbauer, E., Gruber, V., Greinix, H. T., Prochazka, K. T., Thallinger, G. G., Heinemann, A., Beham-Schmid, C., Neumeister, P., Wrodnigg, T. M., Fechter, K. & Deutsch, A. J., 24 Sep 2019, In : International Journal of Molecular Sciences . 20, 19, 4740.

Research output: Contribution to journalArticle

Open Access

Towards a new panel of nitrile hydratases

Grill, B., Schwab, H., Glänzer, M., Steinkellner, G., Strohmeier, G., Pogorevcnik, U., Reicher, K., Gruber, K., Donsbach, K. & Winkler, M., 26 Jun 2019.

Research output: Contribution to conferencePoster

Tris(2-Methoxyphenyl)bismuthine polymorphism characterized by nuclear quadrupole resonance spectroscopy

Scharfetter, H., Fischer, R., Krassnig, P., Thonhofer, M., Theyer, F. & Gösweiner, C., 1 Sep 2019, In : Crystals. 9, 9, 446.

Research output: Contribution to journalArticle

Open Access
2018

Aliphatic hydroxylation and epoxidation of capsaicin by Cytochrome P450 CYP505X

Migglautsch, A. K., Willim, M., Schweda, B., Glieder, A., Breinbauer, R. & Winkler, M., 31 Aug 2018, In : Tetrahedron. 74, p. 6199-6204

Research output: Contribution to journalArticle

Application of Threonine Aldolases for the Asymmetric Synthesis of α-Quaternary α-Amino Acids

Blesl, J., Trobe, M., Anderl, F., Breinbauer, R., Strohmeier, G. A. & Fesko, K., 21 Aug 2018, In : ChemCatChem. 10, 16, p. 3453-3458 6 p.

Research output: Contribution to journalArticle

Open Access

Asymmetric Reductive Carbocyclization Using Engineered Ene Reductases

Heckenbichler, K., Schweiger, A. K., Brandner, L. A., Binter, A., Toplak, M., Macheroux, P., Gruber, K. & Breinbauer, R., 2018, In : Angewandte Chemie / International Edition . 57, p. 7240 –7244

Research output: Contribution to journalArticle

Open Access

Asymmetrische reduktive Carbocyclisierung durch modifizierte En‐Reduktasen

Heckenbichler, K., Schweiger, A. K., Brandner, L. A., Binter, A., Toplak, M., Macheroux, P., Gruber, K. & Breinbauer, R., 2018, In : Angewandte Chemie. 130, p. 7360-7364

Research output: Contribution to journalArticle

Open Access

Atglistatin ameliorates functional decline in heart failure via adipocyte-specific inhibition of adipose triglyceride lipase

Parajuli, N., Takahara, S., Matsumura, N., Kim, T. T., Ferdaoussi, M., Migglautsch, A. K., Zechner, R., Breinbauer, R., Kershaw, E. E. & Dyck, J. R. B., 1 Oct 2018, In : American Journal of Physiology / Heart and Circulatory Physiology. 315, 4, p. H879-H884

Research output: Contribution to journalArticle

Biochemical Characterization and Mechanistic Analysis of the Levoglucosan Kinase from Lipomyces starkeyi

Rother, C., Gutmann, A., Gudiminchi, R., Weber, H., Lepak, A. & Nidetzky, B., 16 Mar 2018, In : ChemBioChem. 19, 6, p. 596-603 8 p.

Research output: Contribution to journalArticle

Bioinformatic analysis of the fold type I PLP-dependent enzymes reveals determinants of reaction specificity in L-threonine aldolase from Aeromonas jandaei

Fesko, K., Suplatov, D. & Svedas, V., 8 May 2018, In : FEBS Open Bio. 16 p.

Research output: Contribution to journalArticle

Open Access

Catalytic and substrate promiscuity of engineered l-threonine aldolase

Fesko, K., 2018.

Research output: Contribution to conferencePoster