Activity: Talk or presentation › Invited talk at conference or symposium › Science to science
In this talk, current experimental approaches to determine mechanical properties and the microstructure of myocardial tissues will be presented. Most studies in the past utilized equibiaxial extension tests on hearts from animals. For myocardial tissues, however, these tests do not yield sufficient quantitative information to formulate a reliable constitutive law. In fact, such data may even suggest that the material is transversely isotropic. Myocardial tissue behaves mechanically orthotropic, which has been demonstrated by the results of simple shear tests in different directions on the passive ventricular myocardium from porcine hearts . Moreover, myocardial tissues undergo complex patterns of tensile, compressive, and, in particular, shear deformations throughout the cardiac cycle. Prerequisites to capture the direction-dependent nonlinear material response involve a combination of biaxial extension test data with different loading protocols, and shear test data at different specimen orientations .