Design Space Definition for a Pharmaceutical Hot-Melt Extrusion and Pelletization Process

Theresa Hörmann (Speaker)

Activity: Talk or presentationTalk at conference or symposiumScience to science


A design of experiments was performed to evaluate the process window (design space) for the production of pellets with immediate release profile of an API.
Period28 Jun 2017
Held at11th PSSRC Annual Meeting
Event typeConference
LocationGraz, Austria
Degree of RecognitionInternational


  • continuous manufacturing
  • pharmaceutical engineering
  • hot-melt extrusion
  • design space definition
  • Quality-by-Design
  • strand pelletization