Biomimetic models of the aortic arch for surgical planning

Activity: Talk or presentationTalk at workshop, seminar or courseScience to public

Description

Cardiovascular diseases (CVD) are one of the main and multifactorial health burdens of our ageing and growing global society. An often-encountered disease (1,7-12,7%) are aortic aneurisms that can lead to life-threatening ruptures. A widely used treatment method is endovascular aneurism repair (EVAR) based on implanting metal stents combined with woven Teflon® or polyethylene terephthalate tubes to exclude blood flow through the diseased vessel. For diagnosis and surgical planning, angiographic imaging techniques (ultrasound, computer tomography, MRI) are used and implant sizes and form are adopted to the patients’ needs. It is therefore of interest to develop and manufacture patient specific aorta models that allow pre-surgical planning and testing of implant properties and performance. For patient specific anatomies such models have been prepared previously using a combination of imaging data, computer aided design (CAD) and additive manufacturing techniques (3D printing). Biological tissue has very peculiar biophysical and mechanical properties due to being extremely complex and hierarchically organized and being composed of protein nanofibers embedded in a polymer matrix. Aortic models that imitate these biomechanical properties have up to now not been manufactured. This presentation gives an overview of recently obtained results in the design and production of patient specific three dimensionally printed aortic models that mimic the biophysical and anatomical properties of healthy and diseased tissue.
Period1 Sep 2021
Event titlePolymer Meeting 14: PM14
Event typeOther
LocationGraz, AustriaShow on map
Degree of RecognitionInternational