Tailor-made resealable micro(bio)reactors providing easy integration of in situ sensors

Martina Viefhues, Shiwen Sun, Donya Valikhani, Bernd Nidetzky, Elwin X. Vrouwe, Torsten Mayr, Juan M. Bolivar

Publikation: Beitrag in einer FachzeitschriftArtikel

Abstract

Flow microreactors utilizing immobilized enzymes are of great interest in biocatalysis development. Most of the common devices are permanently closed, single-use systems, which allow limited physical and chemical surface modifications and evaluation methods. In this paper we will present resealable flowcells that overcome these limitations and moreover allow a quick and easy integration of sensor systems, because of the use of modular building blocks. The devices were utilized to study the enzyme activity of glucose oxidase immobilized on chemically modified glass surfaces under flow conditions, employing integrated optical oxygen sensors for on-line monitoring.

Originalspracheenglisch
Aufsatznummer065012
FachzeitschriftJournal of Micromechanics and Microengineering
Jahrgang27
Ausgabenummer6
DOIs
PublikationsstatusVeröffentlicht - 10 Mai 2017

ASJC Scopus subject areas

  • !!Electronic, Optical and Magnetic Materials
  • !!Mechanics of Materials
  • !!Mechanical Engineering
  • !!Electrical and Electronic Engineering

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