In this chapter, a second-order system, which is subject to different disturbances, is considered. Feedback control laws adopting the continuous twisting and the twisting algorithms are designed such that continuous and saturated control signals are introduced to the system. In the case that a state variable is not available for measurement, estimate information obtained through the robust exact differentiator is incorporated into the design. For the closed loops of the aforementioned techniques, global stability properties are established. Effectiveness of the saturated continuous twisting approach using a comparison with the standard continuous twisting one is illustrated in a real-world application.