Recovery of cis,cis-muconic acid from organic phase after reactive extraction

Jannick Gorden, Tim Zeiner, Gabriele Sadowski, Christoph Brandenbusch

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Abstract

Reactive extraction has been shown as an applicable first step in the downstream processing for the recovery of dicarboxylic acids from aqueous solutions, leading to yields of XRE = 0.95 ± 0.05 for cis,cis-muconic acid. A next step towards a downstream processing concept is the examination of strategies to recover the dicarboxylic acid from the organic phase. A reasonable strategy has to lead to high yields and allow for a recycle of the organic phase for further reactive extraction steps. This work presents two recovery strategies for the cis,cis-muconic acid after reactive extraction. A pH-shift uses the strong pH dependency of the reactive extraction itself. A buffered aqueous phase as re-extraction phase leads to a yield of XREEX = 0.99 ± 0.080 at pH > 7. The second approach is the addition of water soluble amines as an additional reactive component. A complex of water soluble amines and the acid is re-extracted into an aqueous phase. Propylamine showed the best performance (XREEX = 1 ± 0.069) of all water soluble amines investigated. An analysis of the distribution behavior of the water soluble amines showed that a recycle of the organic phase for further reactive extraction steps is feasible for both strategies. The results allow for a further development of an in situ downstream processing concept for biocatalytic produced dicarboxylic acids.

Originalspracheenglisch
Seiten (von - bis)1-8
Seitenumfang8
FachzeitschriftSeparation and purification technology
Jahrgang169
DOIs
PublikationsstatusVeröffentlicht - 1 Sep 2016

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Recovery
Dicarboxylic Acids
Amines
Acids
Water
In situ processing
Propylamines
Processing
muconic acid

Schlagwörter

    ASJC Scopus subject areas

    • Analytische Chemie
    • !!Filtration and Separation

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    Recovery of cis,cis-muconic acid from organic phase after reactive extraction. / Gorden, Jannick; Zeiner, Tim; Sadowski, Gabriele; Brandenbusch, Christoph.

    in: Separation and purification technology, Jahrgang 169, 01.09.2016, S. 1-8.

    Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

    Gorden, Jannick ; Zeiner, Tim ; Sadowski, Gabriele ; Brandenbusch, Christoph. / Recovery of cis,cis-muconic acid from organic phase after reactive extraction. in: Separation and purification technology. 2016 ; Jahrgang 169. S. 1-8.
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