Physicochemical properties and bioactivity of a novel class of cellulosics: 6-deoxy-6-amino cellulose sulfate

Taha Genco, Lidija Fras Zemljič, Matej Bračič, Karin Stana-Kleinschek, Thomas Heinze*

*Korrespondierende/r Autor/in für diese Arbeit

Publikation: Beitrag in einer FachzeitschriftArtikel

Abstract

The physicochemical behavior with emphasis on the charging behavior of 6-deoxy-6-(2-(bis(2-aminoethyl)aminoethyl-amino) cellulose sulfate (BAECS) with degree of substitution (DS) of 1.31 (sulfate moieties) and 0.71 (amino moieties) and of 6-deoxy-6-(2-aminoethyl) cellulose sulfate (AECS, DS Sulf = 1.41, DS DAE = 0.85, DS Tosyl ≈0.09) is studied by using several types of titrations. The amounts of protonated amino groups determined by conductometric titration are 4.02 and 2.53 mmol g -1 for BAECS and AECS, respectively. The amino groups are fully deprotonated at pH ≥ 11, whereas the sulfate moieties determined by polyelectrolyte titration are fully dissociated at this pH value. Furthermore, studies on the antimicrobial and antithrombogenetic efficiencies of the samples are carried out.

Originalspracheenglisch
Seiten (von - bis)539-548
Seitenumfang10
FachzeitschriftMacromolecular Chemistry and Physics
Jahrgang213
Ausgabenummer5
DOIs
PublikationsstatusVeröffentlicht - 16 Mär 2012
Extern publiziertJa

ASJC Scopus subject areas

  • !!Condensed Matter Physics
  • !!Physical and Theoretical Chemistry
  • Organische Chemie
  • !!Polymers and Plastics
  • !!Materials Chemistry

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