Photo-Biocatalysis: Biotransformations in the Presence of Light

Luca Schmermund, Valentina Jurkaš, Fatma Feyza Özgen, Giovanni Davide Barone, Hanna Christiane Büchsenschütz, Christoph K. Winkler, S Schmidt, Robert Kourist, Wolfgang Kroutil

Publikation: Beitrag in einer FachzeitschriftReview eines Fachbereichs (Review article)ForschungBegutachtung

Abstract

Light has received increased attention for various chemical reactions but also in combination with biocatalytic reactions. Because currently only a few enzymatic reactions are known, which per se require light, most transformations involving light and a biocatalyst exploit light either for providing the cosubstrate or cofactor in an appropriate redox state for the biotransformation. In selected cases, a promiscuous activity of known enzymes in the presence of light could be induced. In other approaches, light-induced chemical reactions have been combined with a biocatalytic step, or light-induced biocatalytic reactions were combined with chemical reactions in a linear cascade. Finally, enzymes with a light switchable moiety have been investigated to turn off/on or tune the actual reaction. This Review gives an overview of the various approaches for using light in biocatalysis.

Originalspracheenglisch
Seiten (von - bis)4115-4144
Seitenumfang30
FachzeitschriftACS Catalysis
Jahrgang9
Ausgabenummer5
DOIs
PublikationsstatusVeröffentlicht - 2019

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Chemical reactions
Enzymes
Biotransformation
Biocatalysis
Biocatalysts
Oxidation-Reduction

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    ASJC Scopus subject areas

    • !!Chemistry(all)
    • !!Catalysis

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    Photo-Biocatalysis: Biotransformations in the Presence of Light. / Schmermund, Luca; Jurkaš, Valentina; Özgen, Fatma Feyza; Barone, Giovanni Davide; Büchsenschütz, Hanna Christiane; Winkler, Christoph K.; Schmidt, S; Kourist, Robert; Kroutil, Wolfgang.

    in: ACS Catalysis, Jahrgang 9, Nr. 5, 2019, S. 4115-4144.

    Publikation: Beitrag in einer FachzeitschriftReview eines Fachbereichs (Review article)ForschungBegutachtung

    Schmermund, Luca ; Jurkaš, Valentina ; Özgen, Fatma Feyza ; Barone, Giovanni Davide ; Büchsenschütz, Hanna Christiane ; Winkler, Christoph K. ; Schmidt, S ; Kourist, Robert ; Kroutil, Wolfgang. / Photo-Biocatalysis: Biotransformations in the Presence of Light. in: ACS Catalysis. 2019 ; Jahrgang 9, Nr. 5. S. 4115-4144.
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    AU - Büchsenschütz, Hanna Christiane

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