TY - JOUR
T1 - Pervasive population genomic consequences of genome duplication in Arabidopsis arenosa
AU - Monnahan, Patrick
AU - Kolar, Filip
AU - Baduel, Pierre
AU - Sailer, Christian
AU - Koch, Jordan
AU - Horvath, Robert
AU - Laenen, Benjamin
AU - Schmickl, Roswitha
AU - Paajanen, Pirita
AU - Sramkova, Gabriela
AU - Bohutinska, Magdalena
AU - Arnold, Brian
AU - Weisman, Caroline M.
AU - Marhold, Karol
AU - Slotte, Tanja
AU - Bomblies, Kirsten
AU - Yant, Levi
PY - 2019/3
Y1 - 2019/3
N2 - Ploidy-variable species allow direct inference of the effects of chromosome copy number on fundamental evolutionary processes. While an abundance of theoretical work suggests polyploidy should leave distinct population genomic signatures, empirical data remains sparse. We sequenced ~300 individuals from 39 populations of Arabidopsis arenosa, a naturally diploid-autotetraploid species. We find that the impacts of polyploidy on population genomic processes are subtle yet pervasive, such as reduced efficiency of purifying selection, differences in linked selection and rampant gene flow from diploids. Initial masking of deleterious mutations, faster rates of nucleotide substitution and interploidy introgression likely conspire to shape the evolutionary potential of polyploids.
AB - Ploidy-variable species allow direct inference of the effects of chromosome copy number on fundamental evolutionary processes. While an abundance of theoretical work suggests polyploidy should leave distinct population genomic signatures, empirical data remains sparse. We sequenced ~300 individuals from 39 populations of Arabidopsis arenosa, a naturally diploid-autotetraploid species. We find that the impacts of polyploidy on population genomic processes are subtle yet pervasive, such as reduced efficiency of purifying selection, differences in linked selection and rampant gene flow from diploids. Initial masking of deleterious mutations, faster rates of nucleotide substitution and interploidy introgression likely conspire to shape the evolutionary potential of polyploids.
U2 - 10.1038/s41559-019-0807-4
DO - 10.1038/s41559-019-0807-4
M3 - Article
SN - 2397-334X
VL - 3
SP - 457
EP - 468
JO - Nature Ecology & Evolution
JF - Nature Ecology & Evolution
IS - 3
ER -