Optical coherence tomography: An Alternative Methodology to Monitor Pharmaceutical Coating Processes

Optical coherence tomography (OCT) features a contact-free non-destructive technique, offering high resolution images of internal structures of materials. It represents an alternative process monitoring technology for coating ­processes, which does not depend on calibration models as are required for spectroscopic methods. Due to its high acquisition rate-OCT enables the ­measurement of local parameters of film-coated pellets or tablets even for fast moving samples and therefore, features a perfect in-line process ­monitoring technology.