Optoelectronic neurostimulation is a promising, minimally invasive treatment modality for neuronal damage, in particular for patients with traumatic brain injury. In this work, a newly developed optoelectronic device, a so-called photocap, based on light-activated organic semiconductor structures with high spatial and temporal resolution is investigated. To prove and verify the feasibility of this new technology, a mathematical model was developed, simulating the electrical response of excitable cells to photocap stimulation. In the first step, a comprehensive technical review of the device concept was performed, building the basis for setting up the simulation model. The simulations demonstrate that photocaps may serve as a stimulation device, triggering action potentials in neural or cardiac cells. Our first results show that the model serves as a perfect tool for evaluating and further developing this new technology, showing high potential for introducing new and innovative therapy methods in the field of optoelectronic cell stimulation.
|Titel|| Stud Health Technol Inform |
|Untertitel||dHealth 2020 – Biomedical Informatics for Health and Care|
|Publikationsstatus||Angenommen/In Druck - 2020|
|Veranstaltung||dHealth 2020 - Wien, Österreich|
Dauer: 19 Mai 2020 → 20 Mai 2020
|Zeitraum||19/05/20 → 20/05/20|