Abstract
A method for immobilization of heparin on polymeric material is disclosed, said method comprising selecting a substrate made from a polymeric material, pre-treating said substrate, mounting said substrate into a vacuum chamber, evacuating the vacuum chamber to pressure essentially below 100 Pa, preferably below 1 Pa, selecting a source of NH2 radicals, leaking the NH2 radicals from said source into said vacuum chamber during continuous pumping of said vacuum chamber, interacting said NH2 (NH2) radicals with said substrate made from a polymeric material, evacuating said vacuum chamber, venting said vacuum chamber to atmospheric pressure, and covalent bonding of activated heparin on said substrate.
Titel in Übersetzung | VERFAHREN ZUR IMMOBILISIERUNG EINES POLYMERMATERIALS |
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Originalsprache | englisch |
Veröffentlichungsnummer | EP2997984 |
IPC | A61L 33/ 00 A I |
Prioritätsdatum | 19/09/14 |
Publikationsstatus | Veröffentlicht - 23 März 2016 |
Extern publiziert | Ja |