Functional polysaccharide composite nanoparticles from cellulose acetate and potential applications

Martin R. Kulterer*, Victoria E. Reichel, Rupert Kargl, Stefan Köstler, Velina Sarbova, Thomas Heinze, Karin Stana-Kleinschek, Volker Ribitsch

*Korrespondierende/r Autor/-in für diese Arbeit

Publikation: Beitrag in einer FachzeitschriftArtikelBegutachtung

Abstract

An in situ technique for preparing composite nanoparticles from hydrophobic cellulose acetate and hydrophilic polysaccharides using nanoprecipitation is presented. This technique allows the nanoparticles' surface properties to be tuned very specifically. Spherical, narrow-size-distributed composite nanoparticles of different size, charge, functionality, and increased stability can be generated by using hydroxyethyl cellulose, carboxymethyl cellulose, low molecular weight chitosan, and amino cellulose. The influence of the pH and hydrophilic polysaccharide content in the particle formation is shown. The pH- and ionic strength- effective zeta-potential functions are evidence of the presence of functional polysaccharides at the nanoparticle surface. The in situ technique is compared with the adsorption of hydrophilic polysaccharides onto cellulose acetate nanoparticles in two steps. The great potential of in situ prepared composite nanoparticles in the pharmaceutical industry and bio- or food technology, as carriers of hydrophobic substances in aqueous media and for specific surface modifications, e.g., to selectively introduce strong antimicrobial properties, is illustrated.

Originalspracheenglisch
Seiten (von - bis)1749-1758
Seitenumfang10
FachzeitschriftAdvanced Functional Materials
Jahrgang22
Ausgabenummer8
DOIs
PublikationsstatusVeröffentlicht - 24 Apr. 2012
Extern publiziertJa

ASJC Scopus subject areas

  • Chemie (insg.)
  • Werkstoffwissenschaften (insg.)
  • Physik der kondensierten Materie

Fingerprint

Untersuchen Sie die Forschungsthemen von „Functional polysaccharide composite nanoparticles from cellulose acetate and potential applications“. Zusammen bilden sie einen einzigartigen Fingerprint.

Dieses zitieren