Derivatives of natural organocatalytic cofactors and artificial organocatalytic cofactors as catalysts in enzymes

Publikation: Beitrag in einer FachzeitschriftReview eines Fachbereichs (Review article)Begutachtung

Abstract

Catalytically active non-metal cofactors in enzymes carry out a variety of different reactions. The efforts to develop derivatives of naturally occurring cofactors such as flavins or pyridoxal phosphate and the advances to design new, non-natural cofactors are reviewed here. We report the status quo for enzymes harboring organocatalysts as derivatives of natural cofactors or as artificial ones and their application in the asymmetric synthesis of various compounds.

Originalspracheenglisch
Aufsatznummere202100599
Seitenumfang12
FachzeitschriftChemBioChem
Jahrgang23
Ausgabenummer13
Frühes Online-Datum12 Apr 2022
DOIs
PublikationsstatusVeröffentlicht - 5 Jul 2022

ASJC Scopus subject areas

  • Molekularmedizin
  • Molekularbiologie
  • Biochemie
  • Organische Chemie

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