Creation of a lipase highly selective for trans fatty acids by protein engineering

Henrike B Brundiek, Andrew S Evitt, Robert Kourist, Uwe T Bornscheuer

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Abstract

Sorting out: Protein engineering of lipase CAL-A led to the discovery of mutants with excellent chemoselectivity for the removal of trans and saturated fatty acids from partially hydrogenated vegetable oil. These fatty acids, identified as a major risk factor for human health, can now be removed by enzyme catalysis.

Originalspracheenglisch
Seiten (von - bis)412-4
Seitenumfang3
FachzeitschriftAngewandte Chemie / International Edition
Jahrgang51
Ausgabenummer2
DOIs
PublikationsstatusVeröffentlicht - 9 Jan 2012

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Saturated fatty acids
Trans Fatty Acids
Vegetable oils
Lipases
Lipase
Sorting
Fatty acids
Catalysis
Fatty Acids
Enzymes
Health
Proteins
Plant Oils

Schlagwörter

    Fields of Expertise

    • Human- & Biotechnology

    Dies zitieren

    Creation of a lipase highly selective for trans fatty acids by protein engineering. / Brundiek, Henrike B; Evitt, Andrew S; Kourist, Robert; Bornscheuer, Uwe T.

    in: Angewandte Chemie / International Edition , Jahrgang 51, Nr. 2, 09.01.2012, S. 412-4.

    Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

    Brundiek, Henrike B ; Evitt, Andrew S ; Kourist, Robert ; Bornscheuer, Uwe T. / Creation of a lipase highly selective for trans fatty acids by protein engineering. in: Angewandte Chemie / International Edition . 2012 ; Jahrgang 51, Nr. 2. S. 412-4.
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    abstract = "Sorting out: Protein engineering of lipase CAL-A led to the discovery of mutants with excellent chemoselectivity for the removal of trans and saturated fatty acids from partially hydrogenated vegetable oil. These fatty acids, identified as a major risk factor for human health, can now be removed by enzyme catalysis.",
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