ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks

Gabriela-Luana Bindea; Bernhard Mlecnik; Hubert Hackl; Pornpimol Charoentong; Marie Tosolini; Amos Kirilovsky; Wolf-Herman Fridman; Franck Pagès; Zlatko Trajanoski; Jérôme Galon

doi:10.1093/bioinformatics/btp101

ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks

Gabriela-Luana Bindea, Bernhard Mlecnik, Hubert Hackl, Pornpimol Charoentong, Marie Tosolini, Amos Kirilovsky, Wolf-Herman Fridman, Franck Pagès, Zlatko Trajanoski, Jérôme Galon

Publikation: Beitrag in einer Fachzeitschrift › Artikel › Begutachtung

Abstract

We have developed ClueGO, an easy to use Cytoscape plug-in that strongly improves biological interpretation of large lists of genes. ClueGO integrates Gene Ontology (GO) terms as well as KEGG/BioCarta pathways and creates a functionally organized GO/pathway term network. It can analyze one or compare two lists of genes and comprehensively visualizes functionally grouped terms. A one-click update option allows ClueGO to automatically download the most recent GO/KEGG release at any time. ClueGO provides an intuitive representation of the analysis results and can be optionally used in conjunction with the GOlorize plug-in.

Originalsprache	englisch
Seiten (von - bis)	1091-1093
Fachzeitschrift	Bioinformatics
Jahrgang	25
Ausgabenummer	8
DOIs	https://doi.org/10.1093/bioinformatics/btp101
Publikationsstatus	Veröffentlicht - 2009

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10.1093/bioinformatics/btp101

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abstract = " We have developed ClueGO, an easy to use Cytoscape plug-in that strongly improves biological interpretation of large lists of genes. ClueGO integrates Gene Ontology (GO) terms as well as KEGG/BioCarta pathways and creates a functionally organized GO/pathway term network. It can analyze one or compare two lists of genes and comprehensively visualizes functionally grouped terms. A one-click update option allows ClueGO to automatically download the most recent GO/KEGG release at any time. ClueGO provides an intuitive representation of the analysis results and can be optionally used in conjunction with the GOlorize plug-in.",

author = "Gabriela-Luana Bindea and Bernhard Mlecnik and Hubert Hackl and Pornpimol Charoentong and Marie Tosolini and Amos Kirilovsky and Wolf-Herman Fridman and Franck Pag{\`e}s and Zlatko Trajanoski and J{\'e}r{\^o}me Galon",

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doi = "10.1093/bioinformatics/btp101",

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T1 - ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks

AU - Bindea, Gabriela-Luana

AU - Mlecnik, Bernhard

AU - Hackl, Hubert

AU - Charoentong, Pornpimol

AU - Tosolini, Marie

AU - Kirilovsky, Amos

AU - Fridman, Wolf-Herman

AU - Pagès, Franck

AU - Trajanoski, Zlatko

AU - Galon, Jérôme

PY - 2009

Y1 - 2009

N2 - We have developed ClueGO, an easy to use Cytoscape plug-in that strongly improves biological interpretation of large lists of genes. ClueGO integrates Gene Ontology (GO) terms as well as KEGG/BioCarta pathways and creates a functionally organized GO/pathway term network. It can analyze one or compare two lists of genes and comprehensively visualizes functionally grouped terms. A one-click update option allows ClueGO to automatically download the most recent GO/KEGG release at any time. ClueGO provides an intuitive representation of the analysis results and can be optionally used in conjunction with the GOlorize plug-in.

AB - We have developed ClueGO, an easy to use Cytoscape plug-in that strongly improves biological interpretation of large lists of genes. ClueGO integrates Gene Ontology (GO) terms as well as KEGG/BioCarta pathways and creates a functionally organized GO/pathway term network. It can analyze one or compare two lists of genes and comprehensively visualizes functionally grouped terms. A one-click update option allows ClueGO to automatically download the most recent GO/KEGG release at any time. ClueGO provides an intuitive representation of the analysis results and can be optionally used in conjunction with the GOlorize plug-in.

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DO - 10.1093/bioinformatics/btp101

M3 - Article

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VL - 25

SP - 1091

EP - 1093

JO - Bioinformatics

JF - Bioinformatics

IS - 8

ER -

ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks

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