CHAPTER 14: Microfluidic Systems and Optical Oxygen Sensors: A Perfect Match for Advancing Bioprocessing and Microbiology

Birgit Ungerböck, Torsten Mayr

Publikation: Beitrag in Buch/Bericht/KonferenzbandBeitrag in Buch/BerichtForschungBegutachtung

Abstract

Microfluidic devices provide intriguing tools for biology, biotechnology and life science. The small size with volumes in the L to fL scale and the fine control over the microenvironment offer an opportunity to accelerate research and development in these areas, where oxygen is a key parameter. Quantification of oxygen is therefore essential and optical sensors are ideally suited for this task because they can be downsized and easily integrated into microscale devices. The integrated oxygen-sensitive material can be read-out contactless with light through the channel wall. This chapter represents an overview of the integration and application of optical oxygen sensors into microfluidic devices and microreactors. It introduces microfluidics for biological systems and flags the necessity of oxygen monitoring. Challenges of integration and demands on optical sensor materials and detection systems are discussed. Sensor formats, integration methods and detection principles are reviewed. Microfluidic systems with integrated sensors are categorized by their application in microbioreactors, cell culture and tissue engineering and representative examples are showcased.

Originalspracheenglisch
TitelQuenched-phosphorescence Detection of Molecular Oxygen
UntertitelApplications in Life Sciences
Herausgeber (Verlag)Royal Society of Chemistry
Seiten278-297
Seitenumfang20
Auflage11
DOIs
PublikationsstatusVeröffentlicht - 1 Jan 2018

Publikationsreihe

NameRSC Detection Science
Nummer11
Band2018-January
ISSN (Print)2052-3068
ISSN (elektronisch)2052-3076

Fingerprint

Microbiology
Oxygen sensors
Optical Devices
Microfluidics
Optical sensors
microbiology
Lab-On-A-Chip Devices
Oxygen
sensor
oxygen
Sensors
Cell Engineering
Biological systems
Biotechnology
life science
Tissue engineering
Cell culture
Biological Science Disciplines
biotechnology
Tissue Engineering

ASJC Scopus subject areas

  • Bioengineering
  • !!Pathology and Forensic Medicine
  • !!Chemistry(all)
  • Umweltchemie
  • !!Biochemistry, Genetics and Molecular Biology(all)
  • !!Pollution
  • !!Biochemistry, medical

Dies zitieren

Ungerböck, B., & Mayr, T. (2018). CHAPTER 14: Microfluidic Systems and Optical Oxygen Sensors: A Perfect Match for Advancing Bioprocessing and Microbiology. in Quenched-phosphorescence Detection of Molecular Oxygen: Applications in Life Sciences (11 Aufl., S. 278-297). (RSC Detection Science; Band 2018-January, Nr. 11). Royal Society of Chemistry. https://doi.org/10.1039/9781788013451-00278

CHAPTER 14 : Microfluidic Systems and Optical Oxygen Sensors: A Perfect Match for Advancing Bioprocessing and Microbiology. / Ungerböck, Birgit; Mayr, Torsten.

Quenched-phosphorescence Detection of Molecular Oxygen: Applications in Life Sciences. 11. Aufl. Royal Society of Chemistry, 2018. S. 278-297 (RSC Detection Science; Band 2018-January, Nr. 11).

Publikation: Beitrag in Buch/Bericht/KonferenzbandBeitrag in Buch/BerichtForschungBegutachtung

Ungerböck, B & Mayr, T 2018, CHAPTER 14: Microfluidic Systems and Optical Oxygen Sensors: A Perfect Match for Advancing Bioprocessing and Microbiology. in Quenched-phosphorescence Detection of Molecular Oxygen: Applications in Life Sciences. 11 Aufl., RSC Detection Science, Nr. 11, Bd. 2018-January, Royal Society of Chemistry, S. 278-297. https://doi.org/10.1039/9781788013451-00278
Ungerböck B, Mayr T. CHAPTER 14: Microfluidic Systems and Optical Oxygen Sensors: A Perfect Match for Advancing Bioprocessing and Microbiology. in Quenched-phosphorescence Detection of Molecular Oxygen: Applications in Life Sciences. 11 Aufl. Royal Society of Chemistry. 2018. S. 278-297. (RSC Detection Science; 11). https://doi.org/10.1039/9781788013451-00278
Ungerböck, Birgit ; Mayr, Torsten. / CHAPTER 14 : Microfluidic Systems and Optical Oxygen Sensors: A Perfect Match for Advancing Bioprocessing and Microbiology. Quenched-phosphorescence Detection of Molecular Oxygen: Applications in Life Sciences. 11. Aufl. Royal Society of Chemistry, 2018. S. 278-297 (RSC Detection Science; 11).
@inbook{67051efc97fc4a0da633166cb514b0d2,
title = "CHAPTER 14: Microfluidic Systems and Optical Oxygen Sensors: A Perfect Match for Advancing Bioprocessing and Microbiology",
abstract = "Microfluidic devices provide intriguing tools for biology, biotechnology and life science. The small size with volumes in the L to fL scale and the fine control over the microenvironment offer an opportunity to accelerate research and development in these areas, where oxygen is a key parameter. Quantification of oxygen is therefore essential and optical sensors are ideally suited for this task because they can be downsized and easily integrated into microscale devices. The integrated oxygen-sensitive material can be read-out contactless with light through the channel wall. This chapter represents an overview of the integration and application of optical oxygen sensors into microfluidic devices and microreactors. It introduces microfluidics for biological systems and flags the necessity of oxygen monitoring. Challenges of integration and demands on optical sensor materials and detection systems are discussed. Sensor formats, integration methods and detection principles are reviewed. Microfluidic systems with integrated sensors are categorized by their application in microbioreactors, cell culture and tissue engineering and representative examples are showcased.",
author = "Birgit Ungerb{\"o}ck and Torsten Mayr",
year = "2018",
month = "1",
day = "1",
doi = "10.1039/9781788013451-00278",
language = "English",
series = "RSC Detection Science",
publisher = "Royal Society of Chemistry",
number = "11",
pages = "278--297",
booktitle = "Quenched-phosphorescence Detection of Molecular Oxygen",
address = "United Kingdom",
edition = "11",

}

TY - CHAP

T1 - CHAPTER 14

T2 - Microfluidic Systems and Optical Oxygen Sensors: A Perfect Match for Advancing Bioprocessing and Microbiology

AU - Ungerböck, Birgit

AU - Mayr, Torsten

PY - 2018/1/1

Y1 - 2018/1/1

N2 - Microfluidic devices provide intriguing tools for biology, biotechnology and life science. The small size with volumes in the L to fL scale and the fine control over the microenvironment offer an opportunity to accelerate research and development in these areas, where oxygen is a key parameter. Quantification of oxygen is therefore essential and optical sensors are ideally suited for this task because they can be downsized and easily integrated into microscale devices. The integrated oxygen-sensitive material can be read-out contactless with light through the channel wall. This chapter represents an overview of the integration and application of optical oxygen sensors into microfluidic devices and microreactors. It introduces microfluidics for biological systems and flags the necessity of oxygen monitoring. Challenges of integration and demands on optical sensor materials and detection systems are discussed. Sensor formats, integration methods and detection principles are reviewed. Microfluidic systems with integrated sensors are categorized by their application in microbioreactors, cell culture and tissue engineering and representative examples are showcased.

AB - Microfluidic devices provide intriguing tools for biology, biotechnology and life science. The small size with volumes in the L to fL scale and the fine control over the microenvironment offer an opportunity to accelerate research and development in these areas, where oxygen is a key parameter. Quantification of oxygen is therefore essential and optical sensors are ideally suited for this task because they can be downsized and easily integrated into microscale devices. The integrated oxygen-sensitive material can be read-out contactless with light through the channel wall. This chapter represents an overview of the integration and application of optical oxygen sensors into microfluidic devices and microreactors. It introduces microfluidics for biological systems and flags the necessity of oxygen monitoring. Challenges of integration and demands on optical sensor materials and detection systems are discussed. Sensor formats, integration methods and detection principles are reviewed. Microfluidic systems with integrated sensors are categorized by their application in microbioreactors, cell culture and tissue engineering and representative examples are showcased.

UR - http://www.scopus.com/inward/record.url?scp=85049215001&partnerID=8YFLogxK

U2 - 10.1039/9781788013451-00278

DO - 10.1039/9781788013451-00278

M3 - Chapter

T3 - RSC Detection Science

SP - 278

EP - 297

BT - Quenched-phosphorescence Detection of Molecular Oxygen

PB - Royal Society of Chemistry

ER -