C-5a-substituted validamine type glycosidase inhibitors.

Michael Schalli, Andreas Wolfsgruber, Andres Gonzalez Santana, Christina Tysoe, Roland Fischer, Arnold Stütz, Martin Thonhofer, Stephen G. Withers

Publikation: Beitrag in einer FachzeitschriftArtikel

Abstract

A series of N-alkyl derivs. of the D-galactosidase inhibitor 1,4-di-epi-validamine featuring lipophilic substituents at position C-5a was prepd. and screened for their glycosidase inhibitory properties. Products turned out selective for β-galactosidases as well as β-glucosidases. [on SciFinder(R)]
Originalspracheenglisch
Seiten (von - bis)1-9
Seitenumfang9
FachzeitschriftCarbohydrate Research
Jahrgang440-441
DOIs
PublikationsstatusVeröffentlicht - 2017

Schlagwörter

  • aminodeoxy oligosaccharide prepn glucosidase galactosidase inhibitor validamine glycosidase

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