A fully automated trabecular bone structural analysis tool based on T2* -weighted magnetic resonance imaging

Markus Kraiger, Petros Martirosian, Peter Opriessnig, Frank Eibofner, Hansjoerg Rempp, Michael Hofer, Fritz Schick, Rudolf Stollberger

Publikation: Beitrag in einer FachzeitschriftArtikel

Abstract

One major source affecting the precision of bone structure analysis in quantitative magnetic resonance imaging (qMRI) is inter- and intraoperator variability, inherent in delineating and tracing regions of interest along longitudinal studies. In this paper an automated analysis tool, featuring bone marrow segmentation, region of interest generation, and characterization of cancellous bone of articular joints is presented. In evaluation studies conducted at the knee joint the novel analysis tool significantly decreased the standard error of measurement and improved the sensitivity in detecting minor structural changes. It further eliminated the need of time-consuming user interaction, and thereby increasing reproducibility.

Originalspracheenglisch
Seiten (von - bis)85-94
Seitenumfang10
FachzeitschriftComputerized Medical Imaging and Graphics
Jahrgang36
Ausgabenummer2
DOIs
PublikationsstatusVeröffentlicht - Mär 2012

Schlagwörter

  • MRI
  • Quantification

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