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Erscheinungsjahr

  • 2019
  • 2018
  • 2017

Autor

  • Johannes Khinast
2019

A novel in silico scale-up approach for hot melt extrusion processes

Matic, J., Witschnigg, A., Zagler, M., Eder, S. & Khinast, J., 31 Aug 2019, in : Chemical Engineering Science. 204, S. 257-269

Publikation: Beitrag in einer FachzeitschriftArtikel

At-line validation of optical coherence tomography as in-line/at-line coating thickness measurement method

Wolfgang, M., Peter, A., Wahl, P., Markl, D., Zeitler, J. A. & Khinast, J. G., 15 Dez 2019, in : International Journal of Pharmaceutics. 572

Publikation: Beitrag in einer FachzeitschriftArtikel

Computational Fluid Dynamics-Discrete Element Method Modeling of an Industrial-Scale Wurster Coater

Boehling, P., Khinast, J. G., Jajcevic, D., Davies, C., Carmody, A., Doshi, P., Ende, M. T. A. & Sarkar, A., Jan 2019, in : Journal of Pharmaceutical Sciences . 108, 1, S. 538-550

Publikation: Beitrag in einer FachzeitschriftArtikel

Deriving control parameter settings from process models to control capsule fillers integrated into continuous manufacturing

Wagner, B., Cheong, S. F., Brinz, T. & Khinast, J., 2 Sep 2019, in : Drug Development and Industrial Pharmacy. 45, 9, S. 1523-1536

Publikation: Beitrag in einer FachzeitschriftArtikel

Drying of supported catalysts for high metal concentrations: A reduced parameter model

Noorithaya, A. V., Bishop, C., Sarkar, P., Khinast, J. G. & Glasser, B. J., 12 Okt 2019, in : Chemical Engineering Science. 206, S. 361-374 14 S.

Publikation: Beitrag in einer FachzeitschriftArtikel

Fifty-Eight Years and Counting: High-Impact Publishing in Computational Pharmaceutical Sciences and Mechanism-Based Modeling

Amidon, G. E., Anderson, B. D., Balthasar, J. P., Bergstrom, C. A. S., Huang, S-M., Kasting, G., Kesisoglou, F., Khinast, J. G., Mager, D. E., Roberts, C. J. & Yu, L., Jan 2019, in : Journal of Pharmaceutical Sciences . 108, 1, S. 2-7

Publikation: Beitrag in einer FachzeitschriftArtikel

Heat transfer of dry granular materials in a bladed mixer: Effect of thermal properties and agitation rate

Hartmanshenn, C., Khinast, J. G., Papageorgiou, C. D., Mitchell, C., Quon, J. & Glasser, B. J., 27 Nov 2019, in : AIChE Journal.

Publikation: Beitrag in einer FachzeitschriftArtikel

IMPACT OF RELATIVE HUMIDITY AND POWDER FILLING LEVEL ON THE ELECTROSTATIC CHARGING BEHAVIOUR OF DIFFERENT CAPSULE TYPES

Wutscher, T., Zellnitz, S., Kobler, M., Buttini, F., Andrade, L., Daza, V., Mercandelli, A., Biserni, S., Ecenarro Probst, S., Khinast, J. & Paudel, A., 1 Apr 2019, in : Journal of Aerosol Medicine and Pulmonary Drug Delivery . 32, 2, S. A9-A10

Publikation: Beitrag in einer FachzeitschriftAbstract

Open Access

Industrial scale simulations of tablet coating using gpu based dem: A validation study

Kureck, H. G., Govender, N., Siegmann, E., Böhling, P., Radeke, C. & Khinast, J., 20 Jul 2019, in : Chemical Engineering Science. S. 462-480 19 S.

Publikation: Beitrag in einer FachzeitschriftArtikel

Measurement of granule layer thickness in a spouted bed coating process via optical coherence tomography

Pietsch, S., Peter, A., Wahl, P., Khinast, J. & Heinrich, S., Nov 2019, in : Powder Technology. 356, S. 139-147

Publikation: Beitrag in einer FachzeitschriftArtikel

Measuring bulk density variations in a moving powder bed via terahertz in-line sensing

Stranzinger, S., Faulhammer, E., Li, J., Dong, R., Khinast, J. G., Zeitler, J. A. & Markl, D., 15 Feb 2019, in : Powder Technology. 344, S. 152-160

Publikation: Beitrag in einer FachzeitschriftArtikel

Model-based approach to the design of pharmaceutical roller-compaction processes

Toson, P., Lopes, D. G., Paus, R., Kumar, A., Geens, J., Stibale, S., Quodbach, J., Kleinebudde, P., Hsiao, W-K. & Khinast, J., Dez 2019, in : International Journal of Pharmaceutics: X. 1, 100005.

Publikation: Beitrag in einer FachzeitschriftArtikel

Open Access

Particle-level residence time data in a twin-screw feeder

Toson, P. & Khinast, J. G., Dez 2019, in : Data in Brief . 27, 104672

Publikation: Beitrag in einer FachzeitschriftArtikel

Particle-Level Residence Time Data in a Twin-Screw Feeder

Toson, P. & Khinast, J., 22 Okt 2019

Publikation: Nonprint-FormenDatensätze / Datenbank

Open Access

Performance Characterization of Static Mixers in Precipitating Environments

Kreimer, M., Zettl, M., Aigner, I., Mannschott, T., van der Wel, P., Khinast, J. G. & Krumme, M., Jul 2019, in : Organic Process Research & Devlopment. 23, 7, S. 1308-1320

Publikation: Beitrag in einer FachzeitschriftArtikel

Predicting capsule fill weight from in-situ powder density measurements using terahertz reflection technology

Stranzinger, S., Faulhammer, E., Li, J., Dong, R., Zeitler, J. A., Biserni, S., Calzolari, V., Khinast, J. G. & Markl, D., 1 Dez 2019, in : International Journal of Pharmaceutics: X. 1, 100004.

Publikation: Beitrag in einer FachzeitschriftArtikel

Open Access

Prediction of the anisotropic mechanical properties of compacted powders

Loidolt, P., Ulz, M. H. & Khinast, J., 2019, in : Powder Technology. 345, S. 589-600 12 S.

Publikation: Beitrag in einer FachzeitschriftArtikel

Real-time measurement of coating film thickness

Wolfgang, M., Wahl, P., Sacher, S., Gartshein, E. & Khinas, J. G., 1 Mär 2019, in : Pharmaceutical technology. 43, 3, S. 36-47 12 S.

Publikation: Beitrag in einer FachzeitschriftDiskussion

Sensitivity of a continuous hot-melt extrusion and strand pelletization line to control actions and composition variation

Hörmann, T. R., Rehrl, J., Scheibelhofer, O., Schaden, L. M., Funke, A., Makert, C. & Khinast, J. G., 20 Jul 2019, in : International Journal of Pharmaceutics. 566, S. 239-253 15 S.

Publikation: Beitrag in einer FachzeitschriftArtikel

Shedding light on coatings: Real-time monitoring of coating quality at industrial scale

Sacher, S., Wahl, P., Weissensteiner, M., Wolfgang, M., Pokhilchuk, Y., Looser, B., Thies, J., Raffa, A. & Khinast, J. G., 20 Jul 2019, in : International Journal of Pharmaceutics. 566, S. 57-66

Publikation: Beitrag in einer FachzeitschriftArtikel

Study of the capsule-filling dosator process via calibrated DEM simulations

Madlmeir, S., Loidolt, P. & Khinast, J. G., 15 Aug 2019, in : International Journal of Pharmaceutics. 567

Publikation: Beitrag in einer FachzeitschriftArtikel

The need for new control strategies for particulate matter in parenterals

Poms, J., Sacher, S., Nixdorf, M., Dekner, M., Wallner-Mang, S., Janssen, I., Khinast, J. G. & Schennach, R., 3 Jul 2019, in : Pharmaceutical development and technology. 24, 6, S. 739-750 12 S.

Publikation: Beitrag in einer FachzeitschriftArtikel

Tribo-Charging Behaviour of Inhalable Mannitol Blendswith Salbutamol Sulphate

Zellnitz, S., Pinto, J., Brunsteiner, M., Schröttner, H., Khinast, J. & Paudel, A., 2019, in : Pharmaceutical research. 36, 6, S. 80 11 S., 36:80.

Publikation: Beitrag in einer FachzeitschriftArtikel

Using online content uniformity measurements for rapid automated process development exemplified via an X-ray system

Wagner, B., Brinz, T. & Khinast, J., 3 Jul 2019, in : Pharmaceutical development and technology. 24, 6, S. 775-787

Publikation: Beitrag in einer FachzeitschriftArtikel

2018

3D printing of oral drugs: a new reality or hype?

Hsiao, W. K., Lorber, B., Reitsamer, H. & Khinast, J., 2 Jan 2018, in : Expert opinion on drug delivery. 15, 1, S. 1-4 4 S.

Publikation: Beitrag in einer FachzeitschriftEditorial

A combined DEM & FEM approach for modelling roll compaction process

Mazor, A., Orefice, L., Michrafy, A., de Ryck, A. & Khinast, J. G., Sep 2018, in : Powder Technology. 337, S. 3-16 14 S.

Publikation: Beitrag in einer FachzeitschriftArtikel

A system and a method for constant micro dosing and feeding of powder material

Fathollahi, S., Khinast, J., Klein, T., Besenhard, M. & Slama, E., 11 Apr 2018

Publikation: SchutzrechtPatent

Automation of a dosing-disc capsule filler from the perspective of reliability and safety

Wagner, B., Brinz, T., Otterbach, S. & Khinast, J., 4 Mär 2018, in : Drug Development and Industrial Pharmacy. 44, 3, S. 502-510 9 S.

Publikation: Beitrag in einer FachzeitschriftArtikel

Characterization of the coating and tablet core roughness by means of 3D optical coherence tomography

Khinast, J., Markl, D., Wahl, P., Pichler, H. & Sacher, S., 2018, in : International Journal of Pharmaceutics. S. 459-466

Publikation: Beitrag in einer FachzeitschriftArtikel

Continuous Drying of Pharmaceutical Powders Using a Twin-Screw Extruder

Kreimer, M., Aigner, I., Lepek, D. & Khinast, J., 20 Jul 2018, in : Organic Process Research & Devlopment. 22, 7, S. 813-823 11 S.

Publikation: Beitrag in einer FachzeitschriftArtikel

Control of three different continuous pharmaceutical manufacturing processes: Use of soft sensors

Rehrl, J., Kartunnen, A-P., Nicolaï, N., Hörmann, T., Horn, M., Korhonnen, O., Nopens, I., de Beer, T. & Khinast, J., 30 Mai 2018, in : International Journal of Pharmaceutics. 543, 1-2, S. 60-72

Publikation: Beitrag in einer FachzeitschriftArtikel

Crystal Shape Modification via Cycles of Growth and Dissolution in a Tubular Crystallizer

Neugebauer, P., Besenhard, M., Peter, A., Gruber-Wölfler, H. & Khinast, J., 15 Jun 2018, in : Crystal Growth and Design. 18, 8, S. 4403-4415

Publikation: Beitrag in einer FachzeitschriftArtikel

Detailed modeling and process design of an advanced continuous powder mixer

Toson, P., Siegmann, E., Trogrlic, M., Kureck, H., Khinast, J., Jajcevic, D., Doshi, P., Blackwood, D., Bonnassieux, A., Daugherity, P. D. & am Ende, M. T., 1 Dez 2018, in : International Journal of Pharmaceutics. 552, 1-2, S. 288-300 13 S.

Publikation: Beitrag in einer FachzeitschriftArtikel

Effect of particle shape in grinding mills using a GPU based DEM code

Khinast, J., Govender, N., Rajamani, R. K., Wilke, D. N., Wu, C-Y. & Glasser, B. J., 2018, in : Minerals engineering. S. 71-84

Publikation: Beitrag in einer FachzeitschriftArtikel

Flow of granular materials in a bladed mixer: Effect of particle properties and process parameters on impeller torque and power consumption

Boonkanokwong, V., Frank, R. P., Valliappan, P., Remy, B., Khinast, J. G. & Glasser, B. J., 1 Nov 2018, in : Advanced powder technology. 29, 11, S. 2733-2752 20 S.

Publikation: Beitrag in einer FachzeitschriftArtikel

Hopper flow of irregularly shaped particles (non-convex polyhedra): GPU-based DEM simulation and experimental validation

Khinast, J., Govender, N., Wilke, D. N., Wu, C-Y., Pizette, P. & Xu, W., 2018, in : Chemical Engineering Science. S. 34-51

Publikation: Beitrag in einer FachzeitschriftArtikel

In-line measurement of residence time distribution in melt extrusion via video analysis

Wahl, P. R., Hörl, G., Kaiser, D., Sacher, S., Rupp, C., Shlieout, G., Breitenbach, J., Koscher, G. & Khinast, J. G., 1 Feb 2018, in : Polymer Engineering and Science. 58, 2, S. 170-179 10 S.

Publikation: Beitrag in einer FachzeitschriftArtikel

Large-scale GPU based DEM modeling of mixing using irregularly shaped particles

Khinast, J., Govender, N., Wilke, D. N., Wu, C-Y., Rajamani, R. K. & Glasser, B. J., 2018, in : Advanced powder technology. S. 2476-2490

Publikation: Beitrag in einer FachzeitschriftArtikel

Manufacturing classification system in the real world: factors influencing manufacturing process choices for filed commercial oral solid dosage formulations, case studies from industry and considerations for continuous processing

Khinast, J., Leane, M., Pitt, K., Reynolds, G. K., Dawson, N., Ziegler, I., Szepes, A., Crean, A. M., Agnol, R. D., Broegmann, B., Charlton, S., Davies, C., Gamble, J., Gamlen, M., Hsiao, W. K., Khimyak, Y., Kleinebudde, P., Moreton, C., Oswald, M., Page, S. &5 mehr, Paudel, A., Sahoo, R., Sheehan, S., Stamato, H. & Stone, E., 2018, in : Pharmaceutical development and technology. S. 964-977 13 S.

Publikation: Beitrag in einer FachzeitschriftArtikel