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• Liquid Transport Rates during Binary Collisions of Unequally-sized Particles

  Wu, M., Khinast, J. & Radl, S., 2017, in : Powder Technology. 309, S. 95-109 14 S.

  Publikation: Beitrag in einer Fachzeitschrift › Artikel

  Open Access

  Datei

  • Liquids
  • Computer simulation

• Liquid Transport in Bi-disperse Particle Beds revealed by Direct Numerical Simulations

  Wu, M., Khinast, J. & Radl, S., 14 Sep 2016, S. 1. 1 S.

  Publikation: Konferenzbeitrag › Poster

  Open Access

  Datei

  • Direct numerical simulation
  • Liquids
  • Pharmaceutical Preparations
  • Industry

• Liquid Transport in Bi-disperse Particle Beds revealed by Direct Numerical Simulations

  Wu, M., Khinast, J. & Radl, S., 14 Sep 2016, S. 1-2. 2 S.

  Publikation: Konferenzbeitrag › Abstract

  Open Access

  Datei

  • direct numerical simulation
  • beds
  • liquids
  • liquid bridges
  • engineering

• Light in Powder - Penetration and Information

  Scheibelhofer, O., Wahl, P., Larchevêque, B. & Khinast, J., 21 Mär 2016.

  Publikation: Konferenzbeitrag › Poster

• Influence of Process Route on the Mechanical Properties of Polymer Based Intravaginal Drug Delivery Systems

  Eggenreich, K., Schrank, S., Koscher, G., Nickisch, K., Roblegg, E. & Khinast, J., 2017, in : AIP Conference Proceedings. 1914

  Publikation: Beitrag in einer Fachzeitschrift › Artikel

• Industrial scale simulations of tablet coating using gpu based dem: A validation study

  Kureck, H. G., Govender, N., Siegmann, E., Böhling, P., Radeke, C. & Khinast, J., 20 Jul 2019, in : Chemical Engineering Science. S. 462-480 19 S.

  Publikation: Beitrag in einer Fachzeitschrift › Artikel

  • Tablets
  • Coatings
  • Computational methods
  • Finite difference method
  • Costs

• Impulse-based dynamics for studying quasi-static granular flows: Application to hopper emptying of non-spherical particles

  Toson, P. & Khinast, J. G., 15 Mai 2017, in : Powder Technology. 313, S. 353-360 8 S.

  Publikation: Beitrag in einer Fachzeitschrift › Artikel

  • Hoppers
  • Finite difference method
  • Virtual reality
  • Aspect ratio
  • Robotics

• Improving Pellet Quality in a Pharmaceutical Hot Melt Extrusion Process via PID Control and LOLIMOT-Based MPC

  Rehrl, J., Kirchengast, M., Celikovic, S., Sacher, S., Kruisz, J., Khinast, J. & Horn, M., 2019, in : Journal of pharmaceutical innovation. 12 S.

  Publikation: Beitrag in einer Fachzeitschrift › Artikel

  Open Access

  • Particle Size
  • Linear Models
  • Pharmaceutical Preparations
  • Temperature

• IMPACT OF RELATIVE HUMIDITY AND POWDER FILLING LEVEL ON THE ELECTROSTATIC CHARGING BEHAVIOUR OF DIFFERENT CAPSULE TYPES

  Wutscher, T., Zellnitz, S., Kobler, M., Buttini, F., Andrade, L., Daza, V., Mercandelli, A., Biserni, S., Ecenarro Probst, S., Khinast, J. & Paudel, A., 1 Apr 2019, in : Journal of Aerosol Medicine and Pulmonary Drug Delivery . 32, 2, S. A9-A10

  Publikation: Beitrag in einer Fachzeitschrift › Abstract

• IMPACT OF PARTICLE ENGINEERING ON THE PROCESSABILITY AND AEROSOLIZATION PERFORMANCE OF DPI FORMULATIONS

  Zellnitz, S., Faulhammer, E., Wutscher, T., Khinast, J. G. & Paudel, A., Aug 2017, in : Journal of Aerosol Medicine and Pulmonary Drug Delivery . 30, 4, S. A9-A10

  Publikation: Beitrag in einer Fachzeitschrift › Abstract

• How to measure coating thickness of tablets: Method comparison of optical coherence tomography, near-infrared spectroscopy and weight-, height- and diameter gain

  Wahl, P. R., Peter, A., Wolfgang, M. & Khinast, J. G., 1 Sep 2019, in : European journal of pharmaceutics and biopharmaceutics. 142, S. 344-352 9 S.

  Publikation: Beitrag in einer Fachzeitschrift › Artikel

  • Near-Infrared Spectroscopy
  • Optical Coherence Tomography
  • Tablets
  • Weights and Measures
  • Dosage Forms

• Heat transfer of dry granular materials in a bladed mixer: Effect of thermal properties and agitation rate

  Hartmanshenn, C., Khinast, J. G., Papageorgiou, C. D., Mitchell, C., Quon, J. & Glasser, B. J., 27 Nov 2019, in : AIChE Journal.

  Publikation: Beitrag in einer Fachzeitschrift › Artikel

• Fifty-Eight Years and Counting: High-Impact Publishing in Computational Pharmaceutical Sciences and Mechanism-Based Modeling

  Amidon, G. E., Anderson, B. D., Balthasar, J. P., Bergstrom, C. A. S., Huang, S-M., Kasting, G., Kesisoglou, F., Khinast, J. G., Mager, D. E., Roberts, C. J. & Yu, L., Jan 2019, in : Journal of Pharmaceutical Sciences . 108, 1, S. 2-7

  Publikation: Beitrag in einer Fachzeitschrift › Artikel

• Feasibility study for turret speed operating points in a rotary tablet press

  Martinetz, M., Aigner, I., Rehrl, J., Scheibelhofer, O., Laske, S. & Khinast, J., Mär 2016.

  Publikation: Konferenzbeitrag › (Altdaten) Vortrag oder Präsentation

• Extended validation and verification of XPS/AVL-Fire™, a computational CFD-DEM software platform

  Forgber, T., Toson, P., Madlmeir, S., Kureck, H., Khinast, J. G. & Jajcevic, D., 1 Jan 2019, in : Powder Technology.

  Publikation: Beitrag in einer Fachzeitschrift › Artikel

  • Computational fluid dynamics
  • Fires
  • X ray photoelectron spectroscopy
  • Momentum transfer
  • Drug products

• Establishment of a Molding Procedure to Facilitate Formulation Development for Co-extrudates

  Eder, S., Beretta, M., Witschnigg, A., Koutsamanis, I., Eggenreich, K., Khinast, J. G., Koscher, G., Paudel, A., Nickisch, K., Friedrich, M., Froehlich, E. & Roblegg, E., 1 Nov 2017, in : AAPS PharmSciTech . 18, 8, S. 2971-2976 6 S.

  Publikation: Beitrag in einer Fachzeitschrift › Artikel

  • Vacuum
  • extrusion
  • drugs
  • manufacturing
  • Skin

• Ensuring Tablet Quality via Model-based Control of a Continuous Direct Compaction Process

  Kirchengast, M., Celikovic, S., Rehrl, J., Sacher, S., Kruisz, J., Khinast, J. & Horn, M., 15 Aug 2019, in : International Journal of Pharmaceutics. 2019, 567, S. 1-9 9 S.

  Publikation: Beitrag in einer Fachzeitschrift › Artikel

• Efficient Discrete Element Method Simulation Strategy for Analyzing Large-Scale Agitated Powder Mixers

  Siegmann, E., Jajcevic, D., Radeke, C., Strube, D., Friedrich, K. & Khinast, J. G., 1 Aug 2017, in : Chemie - Ingenieur - Technik. 89, 8, S. 995-1005 11 S.

  Publikation: Beitrag in einer Fachzeitschrift › Artikel

  • Finite difference method
  • Product development
  • Powders
  • Drug products
  • Pharmaceutical Preparations

• Effect of Bubble-Particle Interaction Models on Flow Predictions in Three-Phase Bubble Columns

  Gruber, M. C., Radl, S. & Khinast, J., 26 Feb 2016, in : Chemical Engineering Science. 146, S. 226–243

  Publikation: Beitrag in einer Fachzeitschrift › Artikel

  Open Access

• Dynamic cross-flow filtration: enhanced continuous small-scale solid-liquid separation

  Gursch, J., Hohl, R., Dujmovic, D., Brozio, J., Krumme, M., Rasenack, N. & Khinast, J., 2016, in : Drug Development and Industrial Pharmacy. 42, 6, S. 977-984

  Publikation: Beitrag in einer Fachzeitschrift › Artikel

• Drying of supported catalysts for high metal concentrations: A reduced parameter model

  Noorithaya, A. V., Bishop, C., Sarkar, P., Khinast, J. G. & Glasser, B. J., 12 Okt 2019, in : Chemical Engineering Science. 206, S. 361-374 14 S.

  Publikation: Beitrag in einer Fachzeitschrift › Artikel

  • Catalyst supports
  • Drying
  • Metals
  • Catalysts
  • Nitrates

• Drug–Excipient Interactions in the Solid State: The Role of Different Stress Factors

  Gressl, C., Brunsteiner, M., Davis, A., Landis, M., Pencheva, K., Scrivens, G., Sluggett, G. W., Wood, G. P. F., Gruber-Wölfler, H., Khinast, J. & Paudel, A., 2 Nov 2017, in : Molecular pharmaceutics. 14, 12, S. 4560-4571 11 S.

  Publikation: Beitrag in einer Fachzeitschrift › Artikel

  • Citric Acid
  • Humidity
  • Pharmaceutical Preparations
  • Drug Stability
  • Codeine

• Development of a Model-Based Control Concept for a Direct Compaction Process

  Kruisz, J., Rehrl, J., Martinetz, M., Sacher, S., Horn, M. & Khinast, J., 2016.

  Publikation: Konferenzbeitrag › Poster

• Development of a design space and predictive statistical model for capsule filling of low-fill-weight inhalation products

  Paudel, A., Faulhammer, E., Llusa, M., Wahl, PR., Lawrence, S., Biserni, S., Calzolari, V. & Khinast, J., 1 Feb 2016, in : Drug Development and Industrial Pharmacy. 42, 2, S. 221-230

  Publikation: Beitrag in einer Fachzeitschrift › Artikel

  • Statistical Models
  • Inhalation
  • Capsules
  • Powders
  • Weights and Measures

• Deriving control parameter settings from process models to control capsule fillers integrated into continuous manufacturing

  Wagner, B., Cheong, S. F., Brinz, T. & Khinast, J., 2 Sep 2019, in : Drug Development and Industrial Pharmacy. 45, 9, S. 1523-1536

  Publikation: Beitrag in einer Fachzeitschrift › Artikel

• DEM study of granular transport in partially filled horizontal screw conveyors

  Orefice, L. & Khinast, J. G., Jan 2017, in : Powder Technology. 305, S. 347-356

  Publikation: Beitrag in einer Fachzeitschrift › Artikel

• Decoupling of a Low-Dose Dosator Capsule Filling Process in Dynamic and Static Mode Tests to Understand the Extend of the Effect of Powder and Process Parameters on Capsule Quality Attributes

  Faulhammer, E., Stranzinger, S., Loidolt, P., Calzolari, V., Biserni, S., Srčič, S., Dreu, R., Paudel, A. & Khinast, J., 18 Nov 2016.

  Publikation: Konferenzbeitrag › (Altdaten) Vortrag oder Präsentation

• Decoupling of a low-dose dosator capsule filling process in dynamic and static mode tests

  Stranzinger, S., Faulhammer, E., Srčič, S., Calzolari, V., Biserni, S., Paudel, A. & Khinast, J., 31 Mär 2016.

  Publikation: Konferenzbeitrag › (Altdaten) Vortrag oder Präsentation

• Crystal Engineering in Continuous Plug-Flow Crystallizers

  Neugebauer, P., Besenhard, M., Khinast, J. & Scheibelhofer, O., 10 Okt 2017, in : Crystal Growth and Design.

  Publikation: Beitrag in einer Fachzeitschrift › Artikel

• Continuous Suzuki-Miyaura reactions with novel Ce-Sn-Pd oxides and integrated crystallization as continuous downstream protocol

  Lichtenegger, G. J., Maier, M. C., Khinast, J. & Gruber-Wölfler, H., 3 Aug 2016, in : Journal of Flow Chemistry.

  Publikation: Beitrag in einer Fachzeitschrift › Artikel

• Continuous monitoring of API content, API distribution and crushing strength after tableting via near-infrared chemical imaging

  Wahl, P. R., Pucher, I., Scheibelhofer, O., Kerschhaggl, M., Sacher, S. & Khinast, J. G., 25 Feb 2017, in : International Journal of Pharmaceutics. 518, 1-2, S. 130-137

  Publikation: Beitrag in einer Fachzeitschrift › Artikel

• Continuous Manufacturing of Pharmaceuticals: Chapter 10 - Continuous Melt Extrusion and Direct Pelletization

  Laske, S., Hörmann, T., Witschnigg, A., Koscher, G., Wahl, P., Hsiao, W. K. & Khinast, J., 2017, 1st Aufl. NJ, USA: Wiley & Sons. 337 S. (Advances in Pharmaceutical Technology; Band Continuous Manufacturing of Pharmaceuticals, Nr. 1)

  Publikation: Buch/Bericht/Konferenzband › Buch (Autorenwerk)

• Continuous low-dose feeding of highly active pharmaceutical ingredients in hot-melt extrusion

  Paudel, A., Llusa, M., Mohr, S., Baumgartner, R., Koscher, G. & Khinast, J., 2 Aug 2016, in : Drug Development and Industrial Pharmacy. S. 1360-1364 4 S.

  Publikation: Beitrag in einer Fachzeitschrift › Artikel

  • Extrusion
  • Pharmaceutical Preparations
  • Feeding Methods
  • Powders
  • Suspensions

• Continuous feeding of low-dose APIs via periodic micro dosing

  Faulhammer, E., Khinast, J. & Fathollahi, S., 17 Mai 2016, in : International Journal of Pharmaceutics.

  Publikation: Beitrag in einer Fachzeitschrift › Artikel

• Computational Fluid Dynamics-Discrete Element Method Modeling of an Industrial-Scale Wurster Coater

  Boehling, P., Khinast, J. G., Jajcevic, D., Davies, C., Carmody, A., Doshi, P., Ende, M. T. A. & Sarkar, A., Jan 2019, in : Journal of Pharmaceutical Sciences . 108, 1, S. 538-550

  Publikation: Beitrag in einer Fachzeitschrift › Artikel

• Comparison of video analysis and simulations of a drum coating process

  Boehling, P., Toschkoff, G., Dreu, R., Just, S., Kleinebudde, P., Funke, A., Rehbaum, H. & Khinast, J. G., 15 Jun 2017, in : European Journal of Pharmaceutical Sciences. 104, S. 72-81 10 S.

  Publikation: Beitrag in einer Fachzeitschrift › Artikel

  • Tablets
  • Drug Industry
  • Mechanics

• Comparing particle size distributions of an arbitrary shape

  Scheibelhofer, O., Besenhard, M., Piller, M. & Khinast, J., 16 Feb 2016, in : Powder Technology. 294, S. 134-145

  Publikation: Beitrag in einer Fachzeitschrift › Artikel

• Ce0.495Sn0.495Pd0.01O2 as highly stable and low-leaching catalyst in continuous Suzuki-Miyaura cross-coupling reactions

  Lichtenegger, G. J., Khinast, J. & Gruber-Wölfler, H., 2016.

  Publikation: Konferenzbeitrag › (Altdaten) Vortrag oder Präsentation

• At-line validation of optical coherence tomography as in-line/at-line coating thickness measurement method

  Wolfgang, M., Peter, A., Wahl, P., Markl, D., Zeitler, J. A. & Khinast, J. G., 15 Dez 2019, in : International Journal of Pharmaceutics. 572

  Publikation: Beitrag in einer Fachzeitschrift › Artikel

• A Review of PAT Strategies in Secondary Solid Oral Dosage Manufacturing of Small Molecules

  Laske, S., Paudel, A., Scheibelhofer, O., Sacher, S., Hörmann, T. & Khinast, J., Mär 2017, in : Journal of Pharmaceutical Sciences . 106, 3, S. 667-712 45 S.

  Publikation: Beitrag in einer Fachzeitschrift › Artikel

  • Technology
  • Pharmaceutical Preparations
  • Pressure
  • Temperature
  • Research

• Application of Model-Predictive Control to a Feeding Blending Unit

  Rehrl, J., Kruisz, J., Sacher, S., Horn, M. & Khinast, J., 14 Nov 2016.

  Publikation: Konferenzbeitrag › Poster

• A novel in silico scale-up approach for hot melt extrusion processes

  Matic, J., Witschnigg, A., Zagler, M., Eder, S. & Khinast, J., 31 Aug 2019, in : Chemical Engineering Science. 204, S. 257-269

  Publikation: Beitrag in einer Fachzeitschrift › Artikel

• An investigation of the hydrodynamic similarity of single-spout fluidized beds using CFD-DEM simulations

  Ebrahimi, M., Siegmann, E., Prieling, D., Glasser, B. J. & Khinast, J. G., Okt 2017, in : Advanced powder technology. 28, 10, S. 2465-2481

  Publikation: Beitrag in einer Fachzeitschrift › Artikel

• Analysis of Flow and Mixing in Screw Elements of Corotating Twin-Screw Extruders via SPH

  Eitzlmayr, A., Matic, J. & Khinast, J., Jun 2017, in : AIChE Journal. 63, 6, S. 2451-2463

  Publikation: Beitrag in einer Fachzeitschrift › Artikel

  • Extruders
  • Hydrodynamics
  • Conveying
  • Pressure
  • Geometry

• A Model to Predict Liquid Bridge Formation between Wet Particles Based on Direct Numerical Simulations

  Wu, M., Radl, S. & Khinast, J., 16 Feb 2016, in : AIChE Journal. 62, S. 1877-1897 20 S.

  Publikation: Beitrag in einer Fachzeitschrift › Artikel

  Open Access

  Datei

  • Direct numerical simulation
  • Drainage
  • Neck
  • Liquids
  • Model structures

• A Kernel Interpolation Based Fast Multipole Method for Elastodynamic Problems

  Traub, T., Brenn, G. (Hrsg.), Holzapfel, G. (Hrsg.), von der Linden, W. (Hrsg.), Schanz, M. (Hrsg.) & Khinast, J. (Hrsg.), 2016, Verlag der Technischen Universität Graz. (Monographic Series TU Graz, Computation in Engineering and Science (CES))

  Publikation: Buch/Bericht/Konferenzband › Buch (Autorenwerk)

• A Continuous Operation Concept for a Rotary Tablet Press Using Mass Flow Operating Points

  Martinetz, M., Rehrl, J., Aigner, I., Sacher, S. & Khinast, J., 12 Mai 2017, in : Chemie - Ingenieur - Technik. 89, 8

  Publikation: Beitrag in einer Fachzeitschrift › Artikel