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Forschungsoutput 1981 2019

2019

3-Hydroxytyrosol: A whole cell mediated Bioreduction using a type IV Carboxylate Reductase

Horvat, M. & Winkler, M., 9 Jul 2019.

Publikation: KonferenzbeitragPosterForschung

A cell-free in vitro reduction of carboxylate to aldehyde

Schwarz, A., Strohmeier, G., Eiteljörg, I., Kohrt, J., Howard, R. & Winkler, M., Nov 2019.

Publikation: KonferenzbeitragPosterForschung

A functionally-distinct carboxylic acid reductase (PcCAR4) unearthed from a repertoire of type IV CARs in the white-rot fungus Pycnoporus cinnabarinus

Ling, J. G., Mansor, M. H., Murad, M. A., Khalid, R. M., Quay, D. H-X., Winkler, M. & Bakar, F. D. A., 2019, in : Journal of Biotechnology. 2020, 307, S. 55-62

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Pycnoporus
Fungi
Carboxylic acids
Genes
Enzymes

A Multi-Enzyme System for the In vitro Reduction of Carboxylic Acids to Aldehydes

Strohmeier, G., Schwarz, A., Eiteljörg, I., Kohrt, J., Howard, R. & Winkler, M., Jul 2019.

Publikation: KonferenzbeitragPosterForschung

Capsaicin Metabolite Synthesis by Fungal Cytochrome P450

Willim, M., Bachler, T., Schweda, B., Migglautsch, A. K., Glieder, A., Breinbauer, R. & Winkler, M., 14 Feb 2019.

Publikation: KonferenzbeitragPosterForschung

Carboxylic acid reductases in the white-rot fungus Pycnoporus cinnnabarinus

Ling, J. G., Mansor, M. H., Murad, M. A., Khalid, R. M., Quay, D. H-X., Eiteljörg, I., Stolterfoht, H., Winkler, M. & Bakar, F. D. A., Nov 2019.

Publikation: KonferenzbeitragPosterForschung

Characterization of carboxylate reductases (CARs) for the reduction of aromatic carboxylic acids with integrated in vitro cofactor recycling

Weber, D., Patsch, D., Winkler, M., Turner, N. J. & Rother, D., Nov 2019.

Publikation: KonferenzbeitragPosterForschung

Characterization of Type IV Carboxylate Reductases (CARs) for Whole Cell-Mediated Preparation of 3-Hydroxytyrosol

Horvat, M., Fritsche, S., Kourist, R. & Winkler, M., 19 Mär 2019, in : ChemCatChem. S. 4171-4181

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

carboxylates
Oxidoreductases
preparation
cells
aldehydes

Chimeric Carboxylate Reductases

Stolterfoht, H., Gradischnig, D. & Winkler, M., Nov 2019.

Publikation: KonferenzbeitragPosterForschung

Co-factor demand and regeneration in the enzymatic one-step reduction of carboxylates to aldehydes in cell-free systems

Strohmeier, G., Schwarz, A., Andexer, J. N. & Winkler, M., 28 Okt 2019, (Angenommen/In Druck) in : Journal of Biotechnology. 14 S.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Cell-Free System
Aldehydes
Regeneration
Adenosine Triphosphate
Sinorhizobium meliloti

Combined Enzymatic Decarboxylation and Pd-catalyzed Heck Coupling in Continuous Flow

Grabner, B., Schweiger, A. K., Gavric, K., Kourist, R. & Gruber-Wölfler, H., Sep 2019.

Publikation: KonferenzbeitragPosterForschungBegutachtung

Combining Photo-Organo Redox- and Enzyme Catalysis Facilitates Asymmetric C-H Bond Functionalization

Zhang, W., Fernández-Fueyo, E., Hollmann, F., Leemans Martin, L., Pesic, M., Wardenga, R., Höhne, M. & Schmidt, S., 10 Jan 2019, in : European journal of organic chemistry. 2019, 1, S. 80-84 5 S.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Comparison of two new and a known Type IV fungal Carboxylate reductase

Horvat, M., Fritsche, S. & Winkler, M., Nov 2019.

Publikation: KonferenzbeitragPosterForschung

Cytochrome P450 mediated hydroxylation of ibuprofen using Pichia pastoris as biocatalyst

Rinnofner, C., Kerschbaumer, B., Weber, H., Glieder, A. & Winkler, M., Nov 2019.

Publikation: KonferenzbeitragPosterForschung

Cytochrome P450 mediated hydroxylation of ibuprofen using Pichia pastoris as biocatalyst

Rinnofner, C., Kerschbaumer, B., Weber, H., Glieder, A. & Winkler, M., Apr 2019.

Publikation: KonferenzbeitragPosterForschung

Cytochrome P450 mediated hydroxylation of ibuprofen using Pichia pastoris as biocatalyst

Rinnofner, C., Kerschbaumer, B., Weber, H., Glieder, A. & Winkler, M., 2019, in : Biocatalysis and Agricultural Biotechnology. 17, S. 525-528 4 S.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Open Access
ibuprofen
Hydroxylation
Pichia pastoris
Biocatalysts
Pichia

Discovery of carboxylic acid reductase (CAR) from Thermothelomyces thermophilus and its evaluation for vanillin synthesis

Horvat, M., Fiume, G., Fritsche, S. & Winkler, M., 12 Aug 2019, in : Journal of Biotechnology. 304, S. 44-51

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Carboxylic acids
Substrates
Vanillic Acid
Eugenol
Acids

Enzymatic One-Step Reduction of Carboxylates to Aldehydes with Cell-Free Regeneration of ATP and NADPH

Strohmeier, G., Eiteljörg, I., Schwarz, A. & Winkler, M., 26 Apr 2019, in : Chemistry - a European Journal. 25, 24, S. 6119-6123 5 S.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Open Access
Adenosinetriphosphate
Aldehydes
NADP
Carboxylic Acids
Adenosine Triphosphate

Enzyme-catalyzed synthesis of amides from nitriles

Glänzer, M., Grill, B., Schwab, H., Pogorevcnik, U., Reicher, K., Donsbach, K., Pienaar, D. & Winkler, M., Sep 2019.

Publikation: KonferenzbeitragPosterForschung

Expanding the potential of phenolic acid decarboxylase from Bacillus subtilis by use of non-conventional solvents

Schweiger, A. K., Ríos-Lombardía, N., Winkler, C. K., Schmidt, S., Morís, F., Kroutil, W., González-Sabín, J. & Kourist, R., Jul 2019.

Publikation: KonferenzbeitragPosterForschung

Exploring the biocatalytic potential of a cytochrome P450 from Thermothelomyces thermophila

Fürst, M. J. L. J., Kerschbaumer, B., Rinnofner, C., Migglautsch, A. K., Winkler, M. & Fraaije, M. W., 2019, (Angenommen/In Druck) in : Advanced Synthesis & Catalysis. S. 2487 2496 S.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Form follows function: Structure of the carboxylate reductase from Neurospora crassa (NcCAR)

Daniel, B., Pavkov-Keller, T., Leithold, M., Stolterfoht, H., Winkler, M. & Gruber, K., Nov 2019.

Publikation: KonferenzbeitragPosterForschung

Human drug metabolite synthesis catalysed by recombinant P450 enzymes

Glieder, A., Weninger, A., Schmid, C., Rinnofner, C., Winkler, M., Müller, M., Schürmann, M., Woodley, J., Valero, F., Garcia-Ortega, X., Fürst, M. J. L. J. & Fraaije, M. W., Jun 2019.

Publikation: KonferenzbeitragAbstractForschung

Hydrogen-driven cofactor regeneration for stereoselective whole-cell C=C bond reduction in Cupriavidus necator

Assil Companioni, L., Schmidt, S., Heidinger, P., Schwab, H. & Kourist, R., 19 Mär 2019, in : ChemSusChem. 12, 11, S. 2361-2365 5 S.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

biotransformation
Hydrogen
regeneration
hydrogen
Hydrogenase

Membrane protein production in yeast: Modification of yeast membranes for human membrane protein production

Emmerstorfer-Augustin, A., Wriessnegger, T., Hirz, M., Zellnig, G. & Pichler, H., 9 Feb 2019, Recombinant Protein Production in Yeast: Methods and Protocols. Springer, (Methods in Molecular Biology).

Publikation: Beitrag in Buch/Bericht/KonferenzbandBeitrag in Buch/BerichtForschungBegutachtung

Methanol Independent Expression by Pichia Pastoris Employing De-repression Technologies

Fischer, J. E., Hatzl, A-M., Weninger, A., Schmid, C. & Glieder, A., 2019, in : Journal of visualized experiments . 2019, 143, e58589.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Pichia
Methanol
Technology
Bioreactors
Carbon

Nitrile hydratasees for synthesis of amides from nitriles

Grill, B., Schwab, H., Pogorevcnik, U., Glänzer, M., Reicher, K., Donsbach, K. & Winkler, M., Nov 2019.

Publikation: KonferenzbeitragPosterForschung

Optimizing the heterologous expression of the carboxylic acid reductase from Nocardia otitidiscavium for the reduction of aromatic acids

Weber, D., Patsch, D., Winkler, M., Turner, N. & Rother, D., 9 Jul 2019.

Publikation: KonferenzbeitragPosterForschung

Photo-Biocatalysis: Biotransformations in the Presence of Light

Schmermund, L., Jurkaš, V., Özgen, F. F., Barone, G. D., Büchsenschütz, H. C., Winkler, C. K., Schmidt, S., Kourist, R. & Kroutil, W., 2019, in : ACS Catalysis. 9, 5, S. 4115-4144 30 S.

Publikation: Beitrag in einer FachzeitschriftReview eines Fachbereichs (Review article)ForschungBegutachtung

Chemical reactions
Enzymes
Biotransformation
Biocatalysis
Biocatalysts

Random Mutagenesis-Driven Improvement of Carboxylate Reductase Activity Using an Amino Benzamidoxime-Mediated High-Throughput Assay

Schwendenwein, D., Ressmann, A. K., Dörr, M., Höhne, M., Mihovilovic, M. D., Bornscheuer, U. T., Rudroff, F. & Winkler, M., 6 Jun 2019, in : Advanced Synthesis & Catalysis. 361, 11, S. 2544-2549 6 S.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Mutagenesis
Carboxylic acids
Assays
Oxidoreductases
Throughput

Random mutagenesis of carboxylate reductase enabled by a substrate independent HT-assay

Rudroff, F., Winkler, M., Schwendenwein, D., Ressmann, A. K., Mihovilovic, M. D., Bornscheuer, U. T. & Dörr, M., Jul 2019.

Publikation: KonferenzbeitragPosterForschung

Recombinant lipoxygenases (LOX) and hydroperoxide lyases (HPL) for the synthesis of green leaf volatiles

Stolterfoht, H., Rinnofner, C., Winkler, M. & Pichler, H., 8 Okt 2019, (Angenommen/In Druck) in : Journal of agricultural and food chemistry. 59 S.

Publikation: Beitrag in einer FachzeitschriftReview eines Fachbereichs (Review article)ForschungBegutachtung

Lipoxygenases
lyases
hydroperoxides
lipoxygenase
synthesis

Recombinant lipoxygenases and hydroperoxide lyases for the synthesis of green leaf volatiles

Stolterfoht, H., Rinnofner, C., Winkler, M. & Pichler, H., 2019, (Angenommen/In Druck) in : Journal of agricultural and food chemistry.

Publikation: Beitrag in einer FachzeitschriftReview eines Fachbereichs (Review article)ForschungBegutachtung

Structure elucidation of the carboxylate reductase from Neurospora crassa (NcCAR)

Daniel, B., Pavkov-Keller, T., Leithold, M., Gruber, K., Stolterfoht, H. & Winkler, M., 9 Jul 2019.

Publikation: KonferenzbeitragPosterForschung

Substrate-Independent High-Throughput Assay for the Quantification of Aldehydes

Ressmann, A. K., Schwendenwein, D., Leonhartsberger, S., Mihovilovic, M. D., Bornscheuer, U. T., Winkler, M. & Rudroff, F., 6 Jun 2019, in : Advanced Synthesis & Catalysis. 361, 11, S. 2538-2543 6 S.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Aldehydes
Carboxylic acids
Assays
Throughput
Substrates

Towards a new panel of nitrile hydratases

Grill, B., Schwab, H., Glänzer, M., Steinkellner, G., Strohmeier, G., Pogorevcnik, U., Reicher, K., Gruber, K., Donsbach, K. & Winkler, M., 26 Jun 2019.

Publikation: KonferenzbeitragPosterForschung

Using Deep Eutectic Solvents to Overcome Limited Substrate Solubility in the Enzymatic Decarboxylation of Bio-Based Phenolic Acids

Schweiger, A. K., Ríos-Lombardía, N., Winkler, C. K., Schmidt, S., Morís, F., González-Sabín, J. & Kourist, R., 8 Aug 2019, in : ACS Sustainable Chemistry & Engineering. 7, 19, S. 16364-16370

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

decarboxylation
Eutectics
solubility
Solubility
substrate
2018

A light-driven enzyme cascade reaction for the synthesis of lactones

Büchsenschütz, H. C., Schultes, F., Schmidt, S. & Kourist, R., 9 Apr 2018.

Publikation: KonferenzbeitragPosterForschung

A light-driven enzyme cascade reaction for the synthesis of lactones.

Büchsenschütz, H. C., Schultes, F., Schmidt, S. & Kourist, R., 26 Aug 2018.

Publikation: KonferenzbeitragPosterForschung

Aliphatic hydroxylation and epoxidation of capsaicin by Cytochrome P450 CYP505X

Migglautsch, A. K., Willim, M., Schweda, B., Glieder, A., Breinbauer, R. & Winkler, M., 31 Aug 2018, in : Tetrahedron. 74, S. 6199-6204

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Alternative Binding Mode impairs Enantioselectivity of Arylmalonate Decarboxylase

Schweiger, A. K., Enoki, J., Mügge, C. & Kourist, R., Aug 2018.

Publikation: KonferenzbeitragPosterForschung

A novel assay for the detection of carboxylic acid reductase (CAR) activity in whole cells

Schwendenwein, D., Ressmann, A. K., Mihovilovic, M. D., Bornscheuer, U. T., Dörr, M., Rudroff, F. & Winkler, M., 27 Aug 2018.

Publikation: KonferenzbeitragPosterForschung

Bio-based α,ω functionalized hydrocarbons from multi-step reaction sequences with bio- and metallo-catalysts based on the fatty acid decarboxylase OleTJE

Bojarra, S., Reichert, D., Grote, M., Gómez Baraibar, Á., Dennig, A., Nidetzky, B., Mügge, C. & Kourist, R., Mär 2018, in : ChemCatChem. 10, 5, S. 1192-1201

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

decarboxylation
Carboxy-Lyases
fatty acids
Hydrocarbons
Fatty acids

Biocatalytic oxidation reactions - a Chemist's perspective

Dong, J., Fernández-Fueyo, E., Hollmann, F., Paul, C., Pasic, M., Schmidt, S., Wang, Y., Younes, S. & Zhang, W., Jul 2018, in : Angewandte Chemie / International Edition . 57, 30, S. 9238-9261

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Oxidation
Oxidoreductases
Enzymes
Halogenation
Redox reactions

Carboxylic acid reductase enzymes (CARs)

Winkler, M., 2018, in : Current opinion in chemical biology. 43, S. 23-29

Publikation: Beitrag in einer FachzeitschriftReview eines Fachbereichs (Review article)ForschungBegutachtung