• 8010

    Petersgasse 10-12 Graz

    Österreich

Forschungsoutput 1966 2019

2019

3-Hydroxytyrosol: A whole cell mediated Bioreduction using a type IV Carboxylate Reductase

Horvat, M. & Winkler, M., 9 Jul 2019.

Publikation: KonferenzbeitragPosterForschung

A cell-free in vitro reduction of carboxylate to aldehyde

Schwarz, A., Strohmeier, G., Eiteljörg, I., Kohrt, J., Howard, R. & Winkler, M., Nov 2019.

Publikation: KonferenzbeitragPosterForschung

Adsorption and desorption of self-assembled L-cysteine monolayers on nanoporous gold monitored by in situ resistometry

Hengge, E., Steyskal, E-M., Bachler, R., Dennig, A., Nidetzky, B. & Würschum, R., 18 Nov 2019, in : Beilstein Journal of Nanotechnology . 10, S. 2275-2279 5 S.

Publikation: Beitrag in einer FachzeitschriftShort communicationForschungBegutachtung

Open Access
cysteine
Gold
Cysteine
Monolayers
Desorption

A Multi-Enzyme System for the In vitro Reduction of Carboxylic Acids to Aldehydes

Strohmeier, G., Schwarz, A., Eiteljörg, I., Kohrt, J., Howard, R. & Winkler, M., Jul 2019.

Publikation: KonferenzbeitragPosterForschung

An integrated eco-system for pollution prevention and greening the production chain of small-scale rice-paper production: A case study from Vietnam

Hai, L. T., Thanh Tran, V., Vi, L. Q., Phuong Thao, N. T., Hieu, T. T., Braunegg, S., Schnitzer, H. & Braunegg, G., 9 Okt 2019, in : Journal of cleaner production. 28 S., 118785.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Exhaust gases
Ashes
Farms
Wastewater
Pollution

Characterization of carboxylate reductases (CARs) for the reduction of aromatic carboxylic acids with integrated in vitro cofactor recycling

Weber, D., Patsch, D., Winkler, M., Turner, N. J. & Rother, D., Nov 2019.

Publikation: KonferenzbeitragPosterForschung

Characterization of Type IV Carboxylate Reductases (CARs) for Whole Cell-Mediated Preparation of 3-Hydroxytyrosol

Horvat, M., Fritsche, S., Kourist, R. & Winkler, M., 19 Mär 2019, in : ChemCatChem. S. 4171-4181

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

carboxylates
Oxidoreductases
preparation
cells
aldehydes

Comparison of two new and a known Type IV fungal Carboxylate reductase

Horvat, M., Fritsche, S. & Winkler, M., Nov 2019.

Publikation: KonferenzbeitragPosterForschung

Cytochrome P450 mediated hydroxylation of ibuprofen using Pichia pastoris as biocatalyst

Rinnofner, C., Kerschbaumer, B., Weber, H., Glieder, A. & Winkler, M., Nov 2019.

Publikation: KonferenzbeitragPosterForschung

Cytochrome P450 mediated hydroxylation of ibuprofen using Pichia pastoris as biocatalyst

Rinnofner, C., Kerschbaumer, B., Weber, H., Glieder, A. & Winkler, M., Apr 2019.

Publikation: KonferenzbeitragPosterForschung

Enzymatic One-Step Reduction of Carboxylates to Aldehydes with Cell-Free Regeneration of ATP and NADPH

Strohmeier, G., Eiteljörg, I., Schwarz, A. & Winkler, M., 26 Apr 2019, in : Chemistry - a European Journal. 25, 24, S. 6119-6123 5 S.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Open Access
Adenosinetriphosphate
Aldehydes
NADP
Carboxylic Acids
Adenosine Triphosphate

High-Precision rapid sampling device

Klimacek, M., Scharfetter, H. & Hilber, D., 23 Okt 2019, IPC Nr. EP 3 556 843 A1, Patent Nr. 18168285.7

Publikation: SchutzrechtPatentForschung

Interplay of nucleophilic catalysis with proton transfer in the nitrile reductase QueF from Escherichia coli

Jung, J., Braun, J., Czabany, T. & Nidetzky, B., 14 Jan 2019, in : Catalysis Science & Technology. 9, 3, S. 842-853 12 S.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Open Access
Nitriles
Proton transfer
Catalysis
Escherichia coli
Protons

Nitrile hydratasees for synthesis of amides from nitriles

Grill, B., Schwab, H., Pogorevcnik, U., Glänzer, M., Reicher, K., Donsbach, K. & Winkler, M., Nov 2019.

Publikation: KonferenzbeitragPosterForschung

Optimizing the heterologous expression of the carboxylic acid reductase from Nocardia otitidiscavium for the reduction of aromatic acids

Weber, D., Patsch, D., Winkler, M., Turner, N. & Rother, D., 9 Jul 2019.

Publikation: KonferenzbeitragPosterForschung

Random Mutagenesis-Driven Improvement of Carboxylate Reductase Activity Using an Amino Benzamidoxime-Mediated High-Throughput Assay

Schwendenwein, D., Ressmann, A. K., Dörr, M., Höhne, M., Mihovilovic, M. D., Bornscheuer, U. T., Rudroff, F. & Winkler, M., 6 Jun 2019, in : Advanced Synthesis & Catalysis. 361, 11, S. 2544-2549 6 S.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Mutagenesis
Carboxylic acids
Assays
Oxidoreductases
Throughput

Random mutagenesis of carboxylate reductase enabled by a substrate independent HT-assay

Rudroff, F., Winkler, M., Schwendenwein, D., Ressmann, A. K., Mihovilovic, M. D., Bornscheuer, U. T. & Dörr, M., Jul 2019.

Publikation: KonferenzbeitragPosterForschung

Structure elucidation of the carboxylate reductase from Neurospora crassa (NcCAR)

Daniel, B., Pavkov-Keller, T., Leithold, M., Gruber, K., Stolterfoht, H. & Winkler, M., 9 Jul 2019.

Publikation: KonferenzbeitragPosterForschung

Substrate-Independent High-Throughput Assay for the Quantification of Aldehydes

Ressmann, A. K., Schwendenwein, D., Leonhartsberger, S., Mihovilovic, M. D., Bornscheuer, U. T., Winkler, M. & Rudroff, F., 6 Jun 2019, in : Advanced Synthesis & Catalysis. 361, 11, S. 2538-2543 6 S.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Aldehydes
Carboxylic acids
Assays
Throughput
Substrates

Towards a new panel of nitrile hydratases

Grill, B., Schwab, H., Glänzer, M., Steinkellner, G., Strohmeier, G., Pogorevcnik, U., Reicher, K., Gruber, K., Donsbach, K. & Winkler, M., 26 Jun 2019.

Publikation: KonferenzbeitragPosterForschung

2018

A novel assay for the detection of carboxylic acid reductase (CAR) activity in whole cells

Schwendenwein, D., Ressmann, A. K., Mihovilovic, M. D., Bornscheuer, U. T., Dörr, M., Rudroff, F. & Winkler, M., 27 Aug 2018.

Publikation: KonferenzbeitragPosterForschung

A tailor-made, self-sufficient and recyclable monooxygenase catalyst based on coimmobilized cytochrome P450 BM3 and glucose dehydrogenase

Valikhani, D., Bolivar, J. M., Dennig, A. & Nidetzky, B., 1 Okt 2018, in : Biotechnology and Bioengineering. 115, 10, S. 2416-2425 10 S.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Glucose 1-Dehydrogenase
Mixed Function Oxygenases
Cytochrome P-450 Enzyme System
Bacillus megaterium
Glucose

Biobased, Internally pH-Sensitive Materials: Immobilized Yellow Fluorescent Protein as an Optical Sensor for Spatiotemporal Mapping of pH Inside Porous Matrices

Consolati, T., Bolivar, J. M., Petrasek, Z., Berenguer, J., Hidalgo, A., Guisán, J. M. & Nidetzky, B., 28 Feb 2018, in : ACS Applied Materials & Interfaces. 10, 8, S. 6858-6868 11 S.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Optical sensors
Proteins
pH sensors
Penicillin Amidase
Immobilized Enzymes

Bio-based α,ω functionalized hydrocarbons from multi-step reaction sequences with bio- and metallo-catalysts based on the fatty acid decarboxylase OleTJE

Bojarra, S., Reichert, D., Grote, M., Gómez Baraibar, Á., Dennig, A., Nidetzky, B., Mügge, C. & Kourist, R., Mär 2018, in : ChemCatChem. 10, 5, S. 1192-1201

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

decarboxylation
Carboxy-Lyases
fatty acids
Hydrocarbons
Fatty acids

Biochemical Characterization and Mechanistic Analysis of the Levoglucosan Kinase from Lipomyces starkeyi

Rother, C., Gutmann, A., Gudiminchi, R., Weber, H., Lepak, A. & Nidetzky, B., 16 Mär 2018, in : ChemBioChem. 19, 6, S. 596-603 8 S.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Lipomyces
Glucose-6-Phosphate
Phosphotransferases
Adenosine Diphosphate
Adenosine Triphosphate

Demystifying the Flow: Biocatalytic Reaction Intensification in Microstructured Enzyme Reactors

Bolivar, J. M., Valikhani, D. & Nidetzky, B., 9 Aug 2018, in : Biotechnology Journal.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Immobilized Enzymes
sucrose phosphorylase
Enzymes
Biocatalysis
Biotransformation

Discovery and characterization of the tubercidin biosynthetic pathway from Streptomyces tubercidicus NBRC 13090

Liu, Y., Gong, R., Liu, X., Zhang, P., Zhang, Q., Cai, Y-S., Deng, Z., Winkler, M., Wu, J. & Chen, W., 2018, in : Microbial cell factories . 17, 10 S., 131.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Open Access

Evidence of a sequestered imine intermediate during reduction of nitrile to amine by the nitrile reductase QueF from Escherichia coli

Jung, J. & Nidetzky, B., 1 Jan 2018, in : Journal of Biological Chemistry. 293, 10, S. 3720-3733 14 S.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Nitriles
Imines
Escherichia coli
Amines
Oxidoreductases

Fatty Alcohols: enzymatically from Free fatty Acids

Horvat, M., Zabielska, J., Kourist, R. & Winkler, M., 3 Jul 2018.

Publikation: KonferenzbeitragPosterForschung

Fragrance synthesis via a chemo- & multi enzyme cascade

Rudroff, F., Winkler, M., Entner, M., Schwendenwein, D., Ressmann, A. K. & Mihovilovic, M. D., Jul 2018.

Publikation: KonferenzbeitragPosterForschung

Glycosyltransferase cascades made fit for chemical production: Integrated biocatalytic process for the natural polyphenol C-glucoside nothofagin

Schmölzer, K., Lemmerer, M. & Nidetzky, B., 1 Mär 2018, in : Biotechnology and Bioengineering. 115, 3, S. 545-556 12 S.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Glycosyltransferases
Glucosides
Polyphenols
Phloretin
Glycosylation

Humane Enzyme für die Organische Synthese

Winkler, M., Geier, M., Hanlon, S. P., Nidetzky, B. & Glieder, A., 2018, in : Angewandte Chemie. 130, S. 13592-13610

Publikation: Beitrag in einer FachzeitschriftReview eines Fachbereichs (Review article)ForschungBegutachtung

Human Enzymes for Organic Synthesis

Winkler, M., Geier, M., Hanlon, S. P., Nidetzky, B. & Glieder, A., 2018, in : Angewandte Chemie / International Edition . 57, 41, S. 13406-13423 18 S.

Publikation: Beitrag in einer FachzeitschriftReview eines Fachbereichs (Review article)ForschungBegutachtung

Enzymes
Pharmaceutical Preparations
Xenobiotics
Metabolites
Metabolism
adhesives
sulfates
drugs
aerodynamics
powders

Leloir Glycosyltransferases as Biocatalysts for Chemical Production

Nidetzky, B., Gutmann, A. & Zhong, C., 6 Jul 2018, in : ACS Catalysis. 8, 7, S. 6283-6300 18 S.

Publikation: Beitrag in einer FachzeitschriftReview eines Fachbereichs (Review article)ForschungBegutachtung

Glycosylation
Glycosyltransferases
Biocatalysts
Enzymes
Nucleotides

l-Lactic acid production from glucose and xylose with engineered strains of Saccharomyces cerevisiae: Aeration and carbon source influence yields and productivities

Novy, V., Brunner, B. & Nidetzky, B., 11 Apr 2018, in : Microbial cell factories . 17, 1, 59.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Xylose
Lactic acid
Yeast
Glucose
Saccharomyces cerevisiae
Cellulose 1,4-beta-Cellobiosidase
Cellulose
Hydrolysis
Cellulases
Enzymes

New flavanol O-glycosides in grape and wine

Zerbib, M., Mazauric, J. P., Meudec, E., Le Guernevé, C., Lepak, A., Nidetzky, B., Cheynier, V., Terrier, N. & Saucier, C., 15 Nov 2018, in : Food chemistry. 266, S. 441-448 8 S.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Wine
Catechin
Vitis
flavanols
Glycosides

Pressurized CO2 as a carboxylating agent for the biocatalytic: Ortho -carboxylation of resorcinol

Plasch, K., Hofer, G., Keller, W., Hay, S., Heyes, D. J., Dennig, A., Glueck, S. M. & Faber, K., 1 Jan 2018, in : Green chemistry. 20, 8, S. 1754-1759 6 S.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Carboxylation
Enzymes
enzyme
Benzoic Acid
Carboxy-Lyases

Process intensification for O2-dependent enzymatic transformations in continuous single-phase pressurized flow

Bolivar, J. M., Mannsberger, A., Thomsen, M. S., Tekautz, G. & Nidetzky, B., 4 Dez 2018, in : Biotechnology and Bioengineering.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Oxidoreductases
Biotransformation
Catalase
Pressure
Glucose Oxidase

Single-Particle Studies to Advance the Characterization of Heterogeneous Biocatalysts

Benítez-Mateos, A. I., Nidetzky, B., Bolivar, J. M. & López-Gallego, F., 21 Feb 2018, in : ChemCatChem. 10, 4, S. 654-665 12 S.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Biocatalysts
Immobilized Enzymes
Enzymes
enzymes
Structural integrity

The ABAO assay, a new tool for Carboxylic Acid Reductase engineering

Rudroff, F., Winkler, M., Schwendenwein, D., Ressmann, A. K., Mihovilovic, M. D., Bornscheuer, U. T. & Dörr, M., Jul 2018.

Publikation: KonferenzbeitragPosterForschung

Understanding the silica-based sol-gel encapsulation mechanism of Thermomyces lanuginosus lipase: The role of polyethylenimine

Escobar, S., Bernal, C., Bolivar, J. M., Nidetzky, B., López-Gallego, F. & Mesa, M., 1 Apr 2018, in : Molecular Catalysis. S. 106-113 8 S.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Polyethyleneimine
Lipases
Lipase
Encapsulation
Silicon Dioxide

β-Glucosyl Fluoride as Reverse Reaction Donor Substrate and Mechanistic Probe of Inverting Sugar Nucleotide-Dependent Glycosyltransferases

Lepak, A., Gutmann, A. & Nidetzky, B., 5 Okt 2018, in : ACS Catalysis. 8, 10, S. 9148-9153 6 S.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Flavonoids
Glycosyltransferases
Diphosphates
Uridine
Nucleotides
2017

An ortho C-methylation/O-glycosylation motif on a hydroxy-coumarin scaffold, selectively installed by biocatalysis

Gutmann, A., Schiller, M., Gruber-Khadjawi, M. & Nidetzky, B., 5 Sep 2017, in : Organic & biomolecular chemistry. 15, S. 7917 7924 S.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

A Spring in Performance: Silica Nanosprings Boost Enzyme Immobilization in Microfluidic Channels

Valikhani, D., Bolivar, J. M., Viefhues, M., McIlroy, D. N., Vrouwe, E. X. & Nidetzky, B., 11 Okt 2017, in : ACS Applied Materials & Interfaces. 9, 40, S. 34641-34649 9 S.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Enzyme immobilization
Microfluidics
Silicon Dioxide
Enzymes
Silica

Biocatalytic Cascade of Polyphosphate Kinase and Sucrose Synthase for Synthesis of Nucleotide-Activated Derivatives of Glucose

Kulmer, S. T., Gutmann, A., Lemmerer, M. & Nidetzky, B., 2017, in : Advanced Synthesis & Catalysis. 359, S. 292-301

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Open Access
Sugar (sucrose)
Nucleotides
Nucleosides
Glucose
Diphosphates

Combinatorial optimization strategies to increase Human P450 catalytic Activity in whole cell Biotransformations

Weninger, A., Alkofer, A., Schmid, C., Pranjic, M., Winkler, M. & Glieder, A., Jul 2017.

Publikation: KonferenzbeitragPosterForschung

Debottlenecking enzymatic production of fucosylated HMOs with prokaryotic a1,2-fucosyltransferases

Petschacher, B., Gierlinger, K., Brunner, L., Kuballa, J. & Nidetzky, B., 23 Apr 2017.

Publikation: KonferenzbeitragPosterForschungBegutachtung

Development of an optimization mathematical model by applying an integrated environmental indicator for selecting alternatives in cleaner production programs

Van Tran, T., Schnitzer, H., Braunegg, G. & Hai, L. T., 2017, in : Journal of cleaner production. 154, S. 295-308

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung