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2020

Co-factor demand and regeneration in the enzymatic one-step reduction of carboxylates to aldehydes in cell-free systems

Strohmeier, G., Schwarz, A., Andexer, J. N. & Winkler, M., 10 Jan 2020, in : Journal of Biotechnology. 307, S. 202-207 14 S.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Cell-Free System
Aldehydes
Regeneration
Adenosine Triphosphate
Sinorhizobium meliloti

Enzymes revolutionize the bioproduction of value-added compounds: From enzyme discovery to special applications

Wiltschi, B., Cernava, T., Dennig, A., Galindo, M., Geier, M., Gruber, S., Haberbauer, M., Heidinger, P., Acero, E. H., Kratzer, R., Luley-Goedl, C., Müller, C. A., Pitzer, J., Ribitsch, D., Sauer, M., Schmölzer, K., Schnitzhofer, W., Sensen, C. W., Soh, J., Steiner, K. &3 mehrWinkler, C. K., Winkler, M. & Wriessnegger, T., 22 Jan 2020, in : Biotechnology Advances. S. 107520

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Enzymes
Recovery
Biocontrol
Bioconversion
Biocatalysts

Evaluation of Host-based Molecular Markers for the Early Detection of Human Sepsis

Ullrich, E., Heidinger, P., Soh, J., Villanova, L., Grabuschnig, S., Bachler, T., Hirschböck, E., Sánchez-Heredero, S., Ford, B., Sensen, M., Rosales Rodriguez, I., Schwendenwein, D., Neumeister, P., Zurl, C. J., Krause, R., Lorenz Khol, J. & Sensen, C. W., 1 Feb 2020, in : Journal of Biotechnology.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Assays
Sepsis
Blood
Nucleic acids
Nucleic Acids

Microbiome-Guided Exploration of the Microbial Assemblage of the Exotic Beverage “Insect Tea” Native to Southwestern China

Mao, X., Kusstatscher, P., Li, H., Chen, X., Berg, G., Yang, M. & Cernava, T., Jan 2020, in : Frontiers in Microbiology .

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

2019

A functionally-distinct carboxylic acid reductase (PcCAR4) unearthed from a repertoire of type IV CARs in the white-rot fungus Pycnoporus cinnabarinus

Ling, J. G., Mansor, M. H., Murad, M. A., Khalid, R. M., Quay, D. H-X., Winkler, M. & Bakar, F. D. A., 2019, in : Journal of Biotechnology. 2020, 307, S. 55-62

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Pycnoporus
Fungi
Carboxylic acids
Genes
Enzymes

Characterization of Type IV Carboxylate Reductases (CARs) for Whole Cell-Mediated Preparation of 3-Hydroxytyrosol

Horvat, M., Fritsche, S., Kourist, R. & Winkler, M., 19 Mär 2019, in : ChemCatChem. S. 4171-4181

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

carboxylates
Oxidoreductases
preparation
cells
aldehydes

Cytochrome P450 mediated hydroxylation of ibuprofen using Pichia pastoris as biocatalyst

Rinnofner, C., Kerschbaumer, B., Weber, H., Glieder, A. & Winkler, M., 2019, in : Biocatalysis and Agricultural Biotechnology. 17, S. 525-528 4 S.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Open Access
ibuprofen
Hydroxylation
Pichia pastoris
Biocatalysts
Pichia

Discovery of carboxylic acid reductase (CAR) from Thermothelomyces thermophilus and its evaluation for vanillin synthesis

Horvat, M., Fiume, G., Fritsche, S. & Winkler, M., 12 Aug 2019, in : Journal of Biotechnology. 304, S. 44-51

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Carboxylic acids
Substrates
Vanillic Acid
Eugenol
Acids

Disease incidence in sugar beet fields is correlated with microbial diversity and distinct biological markers

Kusstatscher, P., Cernava, T., Harms, K., Maier, J., Eigner, H., Berg, G. & Zachow, C., 4 Mär 2019, in : Phytobiomes Journal.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Open Access
sugar beet
disease incidence
biomarkers
beets
root rot

Enzymatic One-Step Reduction of Carboxylates to Aldehydes with Cell-Free Regeneration of ATP and NADPH

Strohmeier, G., Eiteljörg, I., Schwarz, A. & Winkler, M., 26 Apr 2019, in : Chemistry - a European Journal. 25, 24, S. 6119-6123 5 S.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Open Access
Adenosinetriphosphate
Aldehydes
NADP
Carboxylic Acids
Adenosine Triphosphate

Exploring the Biocatalytic Potential of a Self‐Sufficient Cytochrome P450 from Thermothelomyces thermophila

Fürst, M. J. L. J., Kerschbaumer, B., Rinnofner, C., Migglautsch, A. K., Winkler, M. & Fraaije, M. W., 2019, in : Advanced Synthesis & Catalysis. 361, 11, S. 2487-2496

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Open Access

Hydrogen-driven cofactor regeneration for stereoselective whole-cell C=C bond reduction in Cupriavidus necator

Assil Companioni, L., Schmidt, S., Heidinger, P., Schwab, H. & Kourist, R., 19 Mär 2019, in : ChemSusChem. 12, 11, S. 2361-2365 5 S.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

biotransformation
Hydrogen
regeneration
hydrogen
Hydrogenase

Microbiome-driven identification of microbial indicators for postharvest diseases of sugar beets

Kusstatscher, P., Zachow, C., Harms, K., Maier, J., Eigner, H., Berg, G. & Cernava, T., 7 Aug 2019, in : Microbiome.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Open Access

Microbiota associated with sclerotia of soilborne fungal pathogens – A novel source of biocontrol agents producing bioactive volatiles

Mülner, P., Bergna, A., Wagner, P., Sarajlić, D., Gstöttenmayr, B., Dietel, K., Grosch, R., Cernava, T. & Berg, G., 1 Jan 2019, in : Phytobiomes Journal. 3, 2, S. 125-136 12 S.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Open Access
biocontrol agent
sclerotia
Microbiota
Rhizoctonia
biological control agents

Random Mutagenesis-Driven Improvement of Carboxylate Reductase Activity Using an Amino Benzamidoxime-Mediated High-Throughput Assay

Schwendenwein, D., Ressmann, A. K., Dörr, M., Höhne, M., Mihovilovic, M. D., Bornscheuer, U. T., Rudroff, F. & Winkler, M., 6 Jun 2019, in : Advanced Synthesis & Catalysis. 361, 11, S. 2544-2549 6 S.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Mutagenesis
Carboxylic acids
Assays
Oxidoreductases
Throughput

Seeds of native alpine plants host unique microbial communities embedded in cross-kingdom networks

Wassermann, B., Cernava, T., Müller, H., Berg, C. & Berg, G., 24 Jul 2019, in : Microbiome.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Open Access

Substrate-Independent High-Throughput Assay for the Quantification of Aldehydes

Ressmann, A. K., Schwendenwein, D., Leonhartsberger, S., Mihovilovic, M. D., Bornscheuer, U. T., Winkler, M. & Rudroff, F., 6 Jun 2019, in : Advanced Synthesis & Catalysis. 361, 11, S. 2538-2543 6 S.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Aldehydes
Carboxylic acids
Assays
Throughput
Substrates
2018

Aliphatic hydroxylation and epoxidation of capsaicin by Cytochrome P450 CYP505X

Migglautsch, A. K., Willim, M., Schweda, B., Glieder, A., Breinbauer, R. & Winkler, M., 31 Aug 2018, in : Tetrahedron. 74, S. 6199-6204

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Asymmetric Reductive Carbocyclization Using Engineered Ene Reductases

Heckenbichler, K., Schweiger, A. K., Brandner, L. A., Binter, A., Toplak, M., Macheroux, P., Gruber, K. & Breinbauer, R., 2018, in : Angewandte Chemie / International Edition . 57, S. 7240 –7244

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Open Access

Asymmetrische reduktive Carbocyclisierung durch modifizierte En‐Reduktasen

Heckenbichler, K., Schweiger, A. K., Brandner, L. A., Binter, A., Toplak, M., Macheroux, P., Gruber, K. & Breinbauer, R., 2018, in : Angewandte Chemie. 130, S. 7360-7364

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Open Access

Biobased, Internally pH-Sensitive Materials: Immobilized Yellow Fluorescent Protein as an Optical Sensor for Spatiotemporal Mapping of pH Inside Porous Matrices

Consolati, T., Bolivar, J. M., Petrasek, Z., Berenguer, J., Hidalgo, A., Guisán, J. M. & Nidetzky, B., 28 Feb 2018, in : ACS Applied Materials & Interfaces. 10, 8, S. 6858-6868 11 S.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Optical sensors
Proteins
pH sensors
Penicillin Amidase
Immobilized Enzymes

Biochemical Characterization and Mechanistic Analysis of the Levoglucosan Kinase from Lipomyces starkeyi

Rother, C., Gutmann, A., Gudiminchi, R., Weber, H., Lepak, A. & Nidetzky, B., 16 Mär 2018, in : ChemBioChem. 19, 6, S. 596-603 8 S.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Lipomyces
Glucose-6-Phosphate
Phosphotransferases
Adenosine Diphosphate
Adenosine Triphosphate

Discovery and characterization of the tubercidin biosynthetic pathway from Streptomyces tubercidicus NBRC 13090

Liu, Y., Gong, R., Liu, X., Zhang, P., Zhang, Q., Cai, Y-S., Deng, Z., Winkler, M., Wu, J. & Chen, W., 2018, in : Microbial cell factories . 17, 10 S., 131.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Open Access

Effect of Noncanonical Amino Acids on Protein-Carbohydrate Interactions: Structure, Dynamics, and Carbohydrate Affinity of a Lectin Engineered with Fluorinated Tryptophan Analogs

Tobola, F., Lelimousin, M., Varrot, A., Gillon, E., Darnhofer, B., Blixt, O., Birner-Gruenberger, R., Imberty, A. & Wiltschi, B., 17 Aug 2018, in : ACS Chemical Biology. 13, 8, S. 2211-2219 9 S.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Lectins
Tryptophan
Carbohydrates
Amino Acids
Proteins

First evaluation of alkylpyrazine application as a novel method to decrease microbial contaminations in processed meat products

Schöck, M., Liebminger, S., Berg, G. & Cernava, T., 3 Apr 2018, in : AMB Express. 8, 54, 7 S.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Open Access

Glycosyltransferase cascades made fit for chemical production: Integrated biocatalytic process for the natural polyphenol C-glucoside nothofagin

Schmölzer, K., Lemmerer, M. & Nidetzky, B., 1 Mär 2018, in : Biotechnology and Bioengineering. 115, 3, S. 545-556 12 S.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Glycosyltransferases
Glucosides
Polyphenols
Phloretin
Glycosylation

Identification of key residues for enzymatic carboxylate reduction

Stolterfoht, H., Steinkellner, G., Schwendenwein, D., Pavkov-Keller, T., Gruber, K. & Winkler, M., 12 Feb 2018, in : Frontiers in Microbiology . 9, 250.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

l-Lactic acid production from glucose and xylose with engineered strains of Saccharomyces cerevisiae: Aeration and carbon source influence yields and productivities

Novy, V., Brunner, B. & Nidetzky, B., 11 Apr 2018, in : Microbial cell factories . 17, 1, 59.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Xylose
Lactic acid
Yeast
Glucose
Saccharomyces cerevisiae

Melatonin minimizes the impact of oxidative stress induced by hydrogen peroxide in Saccharomyces and Non-conventional yeast

Vázquez, J., Grillitsch, K., Daum, G., Mas, A., Torija, M. J. & Beltran, G., 20 Aug 2018, in : Frontiers in Microbiology . 9, AUG, 1933.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Saccharomyces
Melatonin
Hydrogen Peroxide
Oxidative Stress
Yeasts

On the current role of hydratases in biocatalysis

Engleder, M. & Pichler, H., 15 Jul 2018, in : Applied Microbiology and Biotechnology. 102, S. 5841-5858

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Open Access

Perdeuteration of cholesterol for neutron scattering applicatioins using recombinant Pichia pastoris

Mouline, M., Strohmeier, G., Hirz, M., Thompson, K., Rennie, A., Campbell, R. A., Pichler, H., Maric, S., Forsyth, T. & Haertlein, M., 5 Feb 2018, in : Chemistry and Physics of Lipids. 212, S. 80-87

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Plasticity of a holobiont: desiccation induces fasting-like metabolism within the lichen microbiota

Cernava, T., Aschenbrenner, I., Soh, J., Sensen, C. W., Grube, M. & Berg, G., 11 Okt 2018, in : The ISME journal. 10 S.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Open Access

Production of Hydroxynitrile Lyase from Davallia tyermannii (DtHNL) in Komagataella phaffii and Its Immobilization as a CLEA to Generate a Robust Biocatalyst

Lanfranchi, E., Grill, B., Raghoebar, Z., Van Pelt, S., Sheldon, R. A., Steiner, K., Glieder, A. & Winkler, M., 2018, in : ChemBioChem. 19, 4, S. 312-316 10.1002/cbic.201700419.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

mandelonitrile lyase
Immobilization
Enzymes
Ferns
Agrochemicals

Recombinant expression, purification and biochemical characterization of kievitone hydratase from Nectria haematococca

Engleder, M., Horvat, M., Emmerstorfer-Augustin, A., Wriessnegger, T., Gabriel, S., Strohmeier, G., Weber, H., Müller, M., Kaluzna, I., Mink, D., Schürmann, M. & Pichler, H., 8 Feb 2018, in : PLoS ONE.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Open Access

The Impact of Deuteration on Natural and Synthetic Lipids: a Neutron Diffraction Study

Luchini, A., Delhom, R., Demé, B., Laux, V., Mouline, M., Haertlein, M., Pichler, H., Strohmeier, G., Wacklin, H. & Fragneto, G., 1 Aug 2018, in : Colloids and Surfaces / B. S. 126 - 133

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Tomato seeds preferably transmit plant beneficial endophytes

Bergna, A., Cernava, T., Rändler-Kleine, M., Grosch, R., Zachow, C. & Berg, G., 1 Okt 2018, in : Phytobiomes Journal. 2, 4, S. 183-193 11 S.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Open Access
endophytes
tomatoes
bacteria
plant growth
seeds

Whole-cell (+)-ambrein production in the yeast Pichia pastoris

Moser, S., Strohmeier, G., Leitner, E., Plocek, T. J., Vanhessche, K. & Pichler, H., Dez 2018, in : Metabolic Engineering Communications. 7, 9 S., e00077.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Open Access
2017
Biological Control Agents
Rhizosphere
Solanum tuberosum
Pseudomonas
Genome

Complete genome sequence of Pseudomonas corrugata strain RM1-1-4, a stress protecting agent from the rhizosphere of an oilseed rape bait plant

Zachow, C., Müller, H., Laireiter, C. M., Tilcher, R. & Berg, G., 9 Nov 2017, in : Standards in Genomic Sciences. 12, 1, 66.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Rhizosphere
Pseudomonas
Genome
Exopeptidases
Siderophores

Crystal Structure and Catalytic Mechanism of CouO, a Versatile C-Methyltransferase from Streptomyces rishiriensis

Pavkov-Keller, T., Steiner, K., Faber, M., Tengg, M., Schwab, H., Gruber-Khadjawi, M. & Gruber, K., 2017, in : PLoS ONE. 12, S. 1-14 e0171056.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Open Access

Differential sharing and distinct co-occurrence networks among spatially close bacterial microbiota of bark, mosses and lichens

Aschenbrenner, I., Cernava, T., Erlacher, A., Berg, G. & Martin, G., 21 Feb 2017, in : Molecular ecology.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Erratum: Enzyme discovery beyond homology: a unique hydroxynitrile lyase in the Bet v1 superfamily

Lanfranchi, E., Pavkov-Keller, T., Koehler, E-M., Diepold, M., Steiner, K., Darnhofer, B., Hartler, J., Bergh, T. V. D., Joosten, H-J., Gruber-Khadjawi, M., Thallinger, G. G., Birner-Gruenberger, R., Gruber, K., Winkler, M. & Glieder, A., 26 Mai 2017, in : Scientific reports. 7, 46834.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Open Access
mandelonitrile lyase
Enzymes

Four distinct types of E.C. 1.2.1.30 enzymes can catalyze the reduction of carboxylic acids to aldehydes

Stolterfoht, H., Schwendenwein, D., Sensen, C. W., Rudroff, F. & Winkler, M., 2017, in : Journal of Biotechnology. 257, S. 222-232

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Harnessing the microbiomes of Brassica vegetables for health issues

Wassermann, B., Rybakova, D., Müller, C. A. & Berg, G., 15 Dez 2017, in : Scientific reports. 7, 17649

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

IN VIVO SYNTHESIS OF POLYHYDROXYLATED COMPOUNDS FROM A ‘HIDDEN RESERVOIR’ OF TOXIC ALDEHYDE SPECIES

Bayer, T., Wiesinger, T., Milker, S., Winkler, M., Mihovilovic, M. D. & Rudroff, F., 2017, in : ChemCatChem. 9, S. 2919-2923

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Localization of Cholesterol within Supported Lipid Bilayers Made of a Natural Extract of Tailor-Deuterated Phosphatidylcholine

Waldie, S., Lind, T. K., Browning, K., Mouline, M., Haertlein, M., Forsyth, T., Luchini, A., Strohmeier, G., Pichler, H., Maric, S. & Cárdenas, M., 27 Dez 2017, in : Langmuir. 34, 1, S. 472-479 8 S.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Lipid bilayers
Cholesterol
cholesterol
Lipid Bilayers
Phosphatidylcholines

Plant microbial diversity is suggested as the key to future biocontrol and health trends

Berg, G., Köberl, M., Rybakova, D., Müller, H., Grosch, R. & Smalla, K., 1 Mai 2017, in : FEMS microbiology ecology. 93, 5, fix050.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Replacing conventional decontamination of hatching eggs with a natural defense strategy based on antimicrobial, volatile pyrazines

Kusstatscher, P., Cernava, T., Liebminger, S. & Berg, G., Okt 2017, in : Scientific reports. 7, 13253.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Open Access
pyrazines
decontamination
hatching
anti-infective agents
fumigation

Symbiotic interplay of fungi, algae, and bacteria within the lung lichen Lobaria pulmonaria L. Hoffm. as assessed by state-of-the-art metaproteomics

Eymann, C., Lassek, C., Wegner, U., Bernhardt, J., Fritsch, O. A., Fuchs, S., Otto, A., Albrecht, D., Schiefelbein, U., Cernava, T., Aschenbrenner, I., Berg, G., Grube, M. & Riedel, K., 14 Mär 2017, in : Journal of proteome research.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Pulmonaria
Lichens
Algae
Fungi
Bacteria

Walking a Fine Line with Sucrose Phosphorylase: Efficient Single-Step Biocatalytic Production of l-Ascorbic Acid 2-Glucoside from Sucrose

Gudiminchi, R. K. & Nidetzky, B., 18 Jul 2017, in : ChemBioChem. 18, 14, S. 1387-1390 4 S.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

sucrose phosphorylase
Ascorbic Acid
Sucrose
Cosmetics
Protonation