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Forschungsoutput 1990 2019

2019

3-Hydroxytyrosol: A whole cell mediated Bioreduction using a type IV Carboxylate Reductase

Horvat, M. & Winkler, M., 9 Jul 2019.

Publikation: KonferenzbeitragPosterForschung

A cell-free in vitro reduction of carboxylate to aldehyde

Schwarz, A., Strohmeier, G., Eiteljörg, I., Kohrt, J., Howard, R. & Winkler, M., Nov 2019.

Publikation: KonferenzbeitragPosterForschung

A functionally-distinct carboxylic acid reductase (PcCAR4) unearthed from a repertoire of type IV CARs in the white-rot fungus Pycnoporus cinnabarinus

Ling, J. G., Mansor, M. H., Murad, M. A., Khalid, R. M., Quay, D. H-X., Winkler, M. & Bakar, F. D. A., 2019, in : Journal of Biotechnology. 2020, 307, S. 55-62

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Pycnoporus
Fungi
Carboxylic acids
Genes
Enzymes

A Multi-Enzyme System for the In vitro Reduction of Carboxylic Acids to Aldehydes

Strohmeier, G., Schwarz, A., Eiteljörg, I., Kohrt, J., Howard, R. & Winkler, M., Jul 2019.

Publikation: KonferenzbeitragPosterForschung

Capsaicin Metabolite Synthesis by Fungal Cytochrome P450

Willim, M., Bachler, T., Schweda, B., Migglautsch, A. K., Glieder, A., Breinbauer, R. & Winkler, M., 14 Feb 2019.

Publikation: KonferenzbeitragPosterForschung

Carboxylic acid reductases in the white-rot fungus Pycnoporus cinnnabarinus

Ling, J. G., Mansor, M. H., Murad, M. A., Khalid, R. M., Quay, D. H-X., Eiteljörg, I., Stolterfoht, H., Winkler, M. & Bakar, F. D. A., Nov 2019.

Publikation: KonferenzbeitragPosterForschung

Characterization of carboxylate reductases (CARs) for the reduction of aromatic carboxylic acids with integrated in vitro cofactor recycling

Weber, D., Patsch, D., Winkler, M., Turner, N. J. & Rother, D., Nov 2019.

Publikation: KonferenzbeitragPosterForschung

Characterization of Type IV Carboxylate Reductases (CARs) for Whole Cell-Mediated Preparation of 3-Hydroxytyrosol

Horvat, M., Fritsche, S., Kourist, R. & Winkler, M., 19 Mär 2019, in : ChemCatChem. S. 4171-4181

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

carboxylates
Oxidoreductases
preparation
cells
aldehydes

Chimeric Carboxylate Reductases

Stolterfoht, H., Gradischnig, D. & Winkler, M., Nov 2019.

Publikation: KonferenzbeitragPosterForschung

Co-factor demand and regeneration in the enzymatic one-step reduction of carboxylates to aldehydes in cell-free systems

Strohmeier, G., Schwarz, A., Andexer, J. N. & Winkler, M., 28 Okt 2019, (Angenommen/In Druck) in : Journal of Biotechnology. 14 S.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Cell-Free System
Aldehydes
Regeneration
Adenosine Triphosphate
Sinorhizobium meliloti

Comparison of two new and a known Type IV fungal Carboxylate reductase

Horvat, M., Fritsche, S. & Winkler, M., Nov 2019.

Publikation: KonferenzbeitragPosterForschung

Cytochrome P450 mediated hydroxylation of ibuprofen using Pichia pastoris as biocatalyst

Rinnofner, C., Kerschbaumer, B., Weber, H., Glieder, A. & Winkler, M., Nov 2019.

Publikation: KonferenzbeitragPosterForschung

Cytochrome P450 mediated hydroxylation of ibuprofen using Pichia pastoris as biocatalyst

Rinnofner, C., Kerschbaumer, B., Weber, H., Glieder, A. & Winkler, M., Apr 2019.

Publikation: KonferenzbeitragPosterForschung

Cytochrome P450 mediated hydroxylation of ibuprofen using Pichia pastoris as biocatalyst

Rinnofner, C., Kerschbaumer, B., Weber, H., Glieder, A. & Winkler, M., 2019, in : Biocatalysis and Agricultural Biotechnology. 17, S. 525-528 4 S.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Open Access
ibuprofen
Hydroxylation
Pichia pastoris
Biocatalysts
Pichia

Discovery of carboxylic acid reductase (CAR) from Thermothelomyces thermophilus and its evaluation for vanillin synthesis

Horvat, M., Fiume, G., Fritsche, S. & Winkler, M., 12 Aug 2019, in : Journal of Biotechnology. 304, S. 44-51

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Carboxylic acids
Substrates
Vanillic Acid
Eugenol
Acids

Disease incidence in sugar beet fields is correlated with microbial diversity and distinct biological markers

Kusstatscher, P., Cernava, T., Harms, K., Maier, J., Eigner, H., Berg, G. & Zachow, C., 4 Mär 2019, in : Phytobiomes Journal.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Open Access
sugar beet
disease incidence
biomarkers
beets
root rot

Enzymatic One-Step Reduction of Carboxylates to Aldehydes with Cell-Free Regeneration of ATP and NADPH

Strohmeier, G., Eiteljörg, I., Schwarz, A. & Winkler, M., 26 Apr 2019, in : Chemistry - a European Journal. 25, 24, S. 6119-6123 5 S.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Open Access
Adenosinetriphosphate
Aldehydes
NADP
Carboxylic Acids
Adenosine Triphosphate

Enzyme-catalyzed synthesis of amides from nitriles

Glänzer, M., Grill, B., Schwab, H., Pogorevcnik, U., Reicher, K., Donsbach, K., Pienaar, D. & Winkler, M., Sep 2019.

Publikation: KonferenzbeitragPosterForschung

Exploring the biocatalytic potential of a cytochrome P450 from Thermothelomyces thermophila

Fürst, M. J. L. J., Kerschbaumer, B., Rinnofner, C., Migglautsch, A. K., Winkler, M. & Fraaije, M. W., 2019, (Angenommen/In Druck) in : Advanced Synthesis & Catalysis. S. 2487 2496 S.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Form follows function: Structure of the carboxylate reductase from Neurospora crassa (NcCAR)

Daniel, B., Pavkov-Keller, T., Leithold, M., Stolterfoht, H., Winkler, M. & Gruber, K., Nov 2019.

Publikation: KonferenzbeitragPosterForschung

Human drug metabolite synthesis catalysed by recombinant P450 enzymes

Glieder, A., Weninger, A., Schmid, C., Rinnofner, C., Winkler, M., Müller, M., Schürmann, M., Woodley, J., Valero, F., Garcia-Ortega, X., Fürst, M. J. L. J. & Fraaije, M. W., Jun 2019.

Publikation: KonferenzbeitragAbstractForschung

Hydrogen-driven cofactor regeneration for stereoselective whole-cell C=C bond reduction in Cupriavidus necator

Assil Companioni, L., Schmidt, S., Heidinger, P., Schwab, H. & Kourist, R., 19 Mär 2019, in : ChemSusChem. 12, 11, S. 2361-2365 5 S.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

biotransformation
Hydrogen
regeneration
hydrogen
Hydrogenase

Membrane protein production in yeast: Modification of yeast membranes for human membrane protein production

Emmerstorfer-Augustin, A., Wriessnegger, T., Hirz, M., Zellnig, G. & Pichler, H., 9 Feb 2019, Recombinant Protein Production in Yeast: Methods and Protocols. Springer, (Methods in Molecular Biology).

Publikation: Beitrag in Buch/Bericht/KonferenzbandBeitrag in Buch/BerichtForschungBegutachtung

Microbiome-driven identification of microbial indicators for postharvest diseases of sugar beets

Kusstatscher, P., Zachow, C., Harms, K., Maier, J., Eigner, H., Berg, G. & Cernava, T., 7 Aug 2019, in : Microbiome.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Open Access

Nitrile hydratasees for synthesis of amides from nitriles

Grill, B., Schwab, H., Pogorevcnik, U., Glänzer, M., Reicher, K., Donsbach, K. & Winkler, M., Nov 2019.

Publikation: KonferenzbeitragPosterForschung

Optimizing the heterologous expression of the carboxylic acid reductase from Nocardia otitidiscavium for the reduction of aromatic acids

Weber, D., Patsch, D., Winkler, M., Turner, N. & Rother, D., 9 Jul 2019.

Publikation: KonferenzbeitragPosterForschung

Random Mutagenesis-Driven Improvement of Carboxylate Reductase Activity Using an Amino Benzamidoxime-Mediated High-Throughput Assay

Schwendenwein, D., Ressmann, A. K., Dörr, M., Höhne, M., Mihovilovic, M. D., Bornscheuer, U. T., Rudroff, F. & Winkler, M., 6 Jun 2019, in : Advanced Synthesis & Catalysis. 361, 11, S. 2544-2549 6 S.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Mutagenesis
Carboxylic acids
Assays
Oxidoreductases
Throughput

Random mutagenesis of carboxylate reductase enabled by a substrate independent HT-assay

Rudroff, F., Winkler, M., Schwendenwein, D., Ressmann, A. K., Mihovilovic, M. D., Bornscheuer, U. T. & Dörr, M., Jul 2019.

Publikation: KonferenzbeitragPosterForschung

Recombinant lipoxygenases (LOX) and hydroperoxide lyases (HPL) for the synthesis of green leaf volatiles

Stolterfoht, H., Rinnofner, C., Winkler, M. & Pichler, H., 8 Okt 2019, (Angenommen/In Druck) in : Journal of agricultural and food chemistry. 59 S.

Publikation: Beitrag in einer FachzeitschriftReview eines Fachbereichs (Review article)ForschungBegutachtung

Lipoxygenases
lyases
hydroperoxides
lipoxygenase
synthesis

Recombinant lipoxygenases and hydroperoxide lyases for the synthesis of green leaf volatiles

Stolterfoht, H., Rinnofner, C., Winkler, M. & Pichler, H., 2019, (Angenommen/In Druck) in : Journal of agricultural and food chemistry.

Publikation: Beitrag in einer FachzeitschriftReview eines Fachbereichs (Review article)ForschungBegutachtung

Signature taxa indicate the storability of sugar beets before harvest

Kusstatscher, P., Cernava, T., Harms, K., Maier, J., Eigner, H., Berg, G. & Zachow, C., 2019.

Publikation: KonferenzbeitragPosterForschungBegutachtung

Structure elucidation of the carboxylate reductase from Neurospora crassa (NcCAR)

Daniel, B., Pavkov-Keller, T., Leithold, M., Gruber, K., Stolterfoht, H. & Winkler, M., 9 Jul 2019.

Publikation: KonferenzbeitragPosterForschung

Substrate-Independent High-Throughput Assay for the Quantification of Aldehydes

Ressmann, A. K., Schwendenwein, D., Leonhartsberger, S., Mihovilovic, M. D., Bornscheuer, U. T., Winkler, M. & Rudroff, F., 6 Jun 2019, in : Advanced Synthesis & Catalysis. 361, 11, S. 2538-2543 6 S.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Aldehydes
Carboxylic acids
Assays
Throughput
Substrates

Towards a new panel of nitrile hydratases

Grill, B., Schwab, H., Glänzer, M., Steinkellner, G., Strohmeier, G., Pogorevcnik, U., Reicher, K., Gruber, K., Donsbach, K. & Winkler, M., 26 Jun 2019.

Publikation: KonferenzbeitragPosterForschung

2018

Aliphatic hydroxylation and epoxidation of capsaicin by Cytochrome P450 CYP505X

Migglautsch, A. K., Willim, M., Schweda, B., Glieder, A., Breinbauer, R. & Winkler, M., 31 Aug 2018, in : Tetrahedron. 74, S. 6199-6204

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

A novel assay for the detection of carboxylic acid reductase (CAR) activity in whole cells

Schwendenwein, D., Ressmann, A. K., Mihovilovic, M. D., Bornscheuer, U. T., Dörr, M., Rudroff, F. & Winkler, M., 27 Aug 2018.

Publikation: KonferenzbeitragPosterForschung

Asymmetric Reductive Carbocyclization Using Engineered Ene Reductases

Heckenbichler, K., Schweiger, A. K., Brandner, L. A., Binter, A., Toplak, M., Macheroux, P., Gruber, K. & Breinbauer, R., 2018, in : Angewandte Chemie / International Edition . 57, S. 7240 –7244

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Open Access

Asymmetrische reduktive Carbocyclisierung durch modifizierte En‐Reduktasen

Heckenbichler, K., Schweiger, A. K., Brandner, L. A., Binter, A., Toplak, M., Macheroux, P., Gruber, K. & Breinbauer, R., 2018, in : Angewandte Chemie. 130, S. 7360-7364

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Open Access

Biobased, Internally pH-Sensitive Materials: Immobilized Yellow Fluorescent Protein as an Optical Sensor for Spatiotemporal Mapping of pH Inside Porous Matrices

Consolati, T., Bolivar, J. M., Petrasek, Z., Berenguer, J., Hidalgo, A., Guisán, J. M. & Nidetzky, B., 28 Feb 2018, in : ACS Applied Materials & Interfaces. 10, 8, S. 6858-6868 11 S.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Optical sensors
Proteins
pH sensors
Penicillin Amidase
Immobilized Enzymes

Biochemical Characterization and Mechanistic Analysis of the Levoglucosan Kinase from Lipomyces starkeyi

Rother, C., Gutmann, A., Gudiminchi, R., Weber, H., Lepak, A. & Nidetzky, B., 16 Mär 2018, in : ChemBioChem. 19, 6, S. 596-603 8 S.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Lipomyces
Glucose-6-Phosphate
Phosphotransferases
Adenosine Diphosphate
Adenosine Triphosphate

Biological postharvest control in sugar beet

Kusstatscher, P., Cernava, T., Harms, K., Maier, J., Eigner, H., Treffer, D., Berg, G. & Zachow, C., Apr 2018.

Publikation: KonferenzbeitragPosterForschungBegutachtung

Carboxylic acid reductase enzymes (CARs)

Winkler, M., 2018, in : Current opinion in chemical biology. 43, S. 23-29

Publikation: Beitrag in einer FachzeitschriftReview eines Fachbereichs (Review article)ForschungBegutachtung

Combinatorial optimization strategies to increase Human P450 catalytic Activity in whole cell

Weninger, A., Alkofer, A., Schmid, C., Bitter, J., Volpini de Maestri, A., Pranjic, M., Winkler, M. & Glieder, A., Sep 2018.

Publikation: KonferenzbeitragPosterForschung

Discovery and characterization of the tubercidin biosynthetic pathway from Streptomyces tubercidicus NBRC 13090

Liu, Y., Gong, R., Liu, X., Zhang, P., Zhang, Q., Cai, Y-S., Deng, Z., Winkler, M., Wu, J. & Chen, W., 2018, in : Microbial cell factories . 17, 10 S., 131.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Open Access

Effect of Noncanonical Amino Acids on Protein-Carbohydrate Interactions: Structure, Dynamics, and Carbohydrate Affinity of a Lectin Engineered with Fluorinated Tryptophan Analogs

Tobola, F., Lelimousin, M., Varrot, A., Gillon, E., Darnhofer, B., Blixt, O., Birner-Gruenberger, R., Imberty, A. & Wiltschi, B., 17 Aug 2018, in : ACS Chemical Biology. 13, 8, S. 2211-2219 9 S.

Publikation: Beitrag in einer FachzeitschriftArtikelForschungBegutachtung

Lectins
Tryptophan
Carbohydrates
Amino Acids
Proteins

Erratum to: Engineered bidirectional promoters enable rapid multi-gene co-expression optimization (Nature Communications, (2018), 9, 1, (3589), 10.1038/s41467-018-05915-w)

Vogl, T., Kickenweiz, T., Pitzer, J., Sturmberger, L., Weninger, A., Biggs, B. W., Köhler, E. M., Baumschlager, A., Fischer, J. E., Hyden, P., Wagner, M., Baumann, M., Borth, N., Geier, M., Ajikumar, P. K. & Glieder, A., 1 Dez 2018, in : Nature Communications. 9, 1, 4566.

Publikation: Beitrag in einer FachzeitschriftDiskussionForschungBegutachtung

files
genes
Publications
Genes
communication